{"id":"W2108674745","doi":"10.1093/hmg/11.25.3135","title":"The Bloom syndrome helicase BLM interacts with TRF2 in ALT cells and promotes telomeric DNA synthesis","year":2002,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":196,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Telomere; Biology; Helicase; Telomerase; Bloom syndrome; Molecular biology; Homologous recombination; Transfection; DNA; Cell biology; Cell culture; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001453201,0.0002905476,0.000372464,0.0001661513,0.0001766492,0.00008287736,0.0001873829,0.00009367414,0.00009686061],"category_scores_gemma":[0.00008187567,0.0002074432,0.00006289263,0.0003154736,0.0002787307,0.00003478046,0.00007252686,0.0002575528,0.00004305186],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003825931,"about_ca_system_score_gemma":0.00002867711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003331957,"about_ca_topic_score_gemma":0.00006324875,"domain_scores_codex":[0.9982785,0.0001065397,0.0003535132,0.0004438756,0.0003513905,0.0004661925],"domain_scores_gemma":[0.9988546,0.0001296789,0.0001012284,0.0006169551,0.00006776762,0.0002297664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001561323,0.001056382,0.008622527,0.0004080502,0.0003024692,0.009682107,0.002998588,0.00004067575,0.9256967,0.0001328678,0.0004506916,0.05045278],"study_design_scores_gemma":[0.004348775,0.00327239,0.1733558,0.001428014,0.0007070091,0.005121988,0.001268913,0.002592831,0.7980684,0.0002563421,0.007996045,0.001583542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994369,0.004047137,0.00004316317,0.0004178958,0.0000412165,0.0005482979,0.000005435173,0.00004578278,0.0004820689],"genre_scores_gemma":[0.9971265,0.001031484,0.0009353758,0.0003625439,0.00003136134,0.00003446414,0.000004041532,0.0000626637,0.0004115283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1647332,"threshold_uncertainty_score":0.8459289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01440219483032144,"score_gpt":0.229552756939598,"score_spread":0.2151505621092766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}