{"id":"W2108677800","doi":"10.1093/emboj/cdg334","title":"Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking","year":2003,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; BC Children's Hospital; Montreal Neurological Institute and Hospital; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of British Columbia","funders":"","keywords":"AMPA receptor; Endocytic cycle; Biology; Clathrin; Cell biology; Endocytosis; Internalization; Dynein; Dynamin; Receptor; Glutamate receptor; Microtubule; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005634199,0.00007724124,0.00008365077,0.000019176,0.00009270132,0.00001546408,0.0001118959,0.00005999667,0.000009767399],"category_scores_gemma":[0.0001723298,0.00004299165,0.00006376299,0.00006839107,0.00007388167,0.000002992551,0.00001283975,0.000194649,5.009911e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000541603,"about_ca_system_score_gemma":0.0000426593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003562342,"about_ca_topic_score_gemma":0.00002150622,"domain_scores_codex":[0.9991689,0.0002433184,0.0002271155,0.0001184897,0.0001091242,0.0001330227],"domain_scores_gemma":[0.99968,0.00001529414,0.0001117339,0.0001274872,0.00002729434,0.00003817836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000357893,0.00004882699,0.005100116,0.000006450777,0.0000092957,0.0000042146,0.0001895647,0.0001747886,0.9931606,0.0001843015,0.000009707331,0.0007542519],"study_design_scores_gemma":[0.00772725,0.001361735,0.2011339,0.0002316581,0.0001128079,0.001077914,0.000727105,0.0007591664,0.7669653,0.001546414,0.01781769,0.0005390941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984369,0.0003342443,0.0005650698,0.0002218982,0.00008923917,0.0001632881,0.000002909409,0.000001991784,0.0001844341],"genre_scores_gemma":[0.9996361,0.0001026569,0.00007796883,0.00004557822,0.0000714703,0.000003242271,0.00001776092,0.000006313783,0.00003891196],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2261953,"threshold_uncertainty_score":0.1753149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01245389058136283,"score_gpt":0.2206918609093107,"score_spread":0.2082379703279479,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}