{"id":"W2108778702","doi":"10.1016/s1701-2163(15)30410-2","title":"A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of Alendronate on Bone Mineral Density and Bone Remodelling in Perimenopausal Women With Low Bone Mineral Density","year":2014,"lang":"en","type":"article","venue":"Journal of Obstetrics and Gynaecology Canada","topic":"Bone health and osteoporosis research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lakehead University; NOSM University; St. Joseph's Care Group; University of Toronto; McMaster University","funders":"Pfizer; Teva Pharmaceutical Industries; Eli Lilly and Company; Amgen","keywords":"Medicine; Bone mineral; Bone remodeling; Placebo; Bone density; Double blind; Randomized controlled trial; Dentistry; Osteoporosis; Internal medicine; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00179531,0.001607252,0.006249847,0.0008269996,0.00093365,0.0009851777,0.001169204,0.003095229,0.007680438],"category_scores_gemma":[0.002624864,0.001279932,0.00205412,0.0007253043,0.002253367,0.001256723,0.0007233198,0.002750716,0.001027885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006162117,"about_ca_system_score_gemma":0.001838299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001610045,"about_ca_topic_score_gemma":0.002872804,"domain_scores_codex":[0.9991818,0.0003417897,0.00009894262,0.0001720624,0.00007967766,0.0001256953],"domain_scores_gemma":[0.998563,0.0004839972,0.0002079689,0.0001648111,0.0001101068,0.0004701017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9889293,0.005518869,0.0001736317,0.0003293543,0.0003238164,0.00002162886,0.00002405363,0.00005028482,0.001325503,0.00003088194,0.0001044775,0.003168129],"study_design_scores_gemma":[0.9771988,0.02187352,0.0004123863,0.000008613658,0.0001925686,0.000007527977,0.000006141262,0.00005873341,0.0001052906,0.00002874003,0.0001024142,0.000005237213],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983293,0.004263968,0.001063125,0.0007435571,0.0008979636,0.007130263,0.00103889,0.0001627057,0.00140647],"genre_scores_gemma":[0.9763489,0.003924978,0.003047341,0.001670568,0.0008809475,0.009344784,0.0009864953,0.0000345564,0.003761513],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007680438,"threshold_uncertainty_score":0.02569366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01424315885301096,"score_gpt":0.2779480935590954,"score_spread":0.2637049347060845,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}