{"id":"W2108911843","doi":"10.1124/mol.112.079277","title":"Extracellular Quaternary Ammonium Blockade of Transient Receptor Potential Vanilloid Subtype 1 Channels Expressed in Xenopus laevis Oocytes","year":2012,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Xenopus; Transient receptor potential channel; Extracellular; Cell biology; Chemistry; Blockade; Receptor; Salientia; Biology; Neuroscience; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005008596,0.0003036055,0.0006247742,0.0003051621,0.0003807925,0.0008315049,0.0007351744,0.0004529635,0.001999224],"category_scores_gemma":[0.0005199745,0.0002451735,0.0003896869,0.0002879128,0.0005266241,0.0007034936,0.0002042025,0.0009551134,0.0004725302],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009159402,"about_ca_system_score_gemma":0.0006675902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003320843,"about_ca_topic_score_gemma":0.004577537,"domain_scores_codex":[0.9995399,0.00007664935,0.00005128778,0.00005436652,0.0001065241,0.0001713869],"domain_scores_gemma":[0.9997371,0.0001140665,0.00004765165,0.000029384,0.00003838237,0.00003338604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003301978,0.00002697476,0.00004434726,0.00004948894,0.000007278189,0.00005333387,0.00004694146,0.00005816377,0.9980135,0.0007376142,0.00004938367,0.0005828462],"study_design_scores_gemma":[0.00007398964,0.0002171112,0.0005837822,0.000006961918,0.00001462077,0.00008160094,0.00003819617,0.000741168,0.9969128,0.00008232341,0.001242373,0.000004976379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917882,0.001509154,0.00188923,0.000241154,0.000108829,0.00005326743,0.0002833687,0.0001051374,0.004021685],"genre_scores_gemma":[0.9920358,0.001214947,0.0018316,0.00007559398,0.00005434797,0.00003773679,0.000314606,0.00006280196,0.004372559],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003320843,"threshold_uncertainty_score":0.006688058,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01978340323268856,"score_gpt":0.2730842534278539,"score_spread":0.2533008501951653,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}