{"id":"W2108932832","doi":"10.1093/annonc/mdp253","title":"Immunotherapy of distant metastatic disease","year":2009,"lang":"en","type":"review","venue":"Annals of Oncology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":57,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sunnybrook Health Science Centre; Hotel Dieu Hospital","funders":"","keywords":"Medicine; Immunotherapy; Melanoma; CD137; Immunology; Metastatic melanoma; Monoclonal antibody; Chimeric antigen receptor; Clinical trial; Antigen; Adoptive cell transfer; Oncology; T cell; Cancer research; Internal medicine; Antibody; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008435274,0.000569316,0.004071218,0.0004786366,0.00008445474,0.000005519079,0.0007959525,0.0004529606,0.000915135],"category_scores_gemma":[0.0002118207,0.0004360024,0.001501225,0.0003543219,0.0007121954,0.00007636741,0.00007820777,0.0005271851,0.00016404],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004319311,"about_ca_system_score_gemma":0.001274807,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003731541,"about_ca_topic_score_gemma":0.000001853637,"domain_scores_codex":[0.9953538,0.0018255,0.001785823,0.0004156917,0.00007120982,0.0005480014],"domain_scores_gemma":[0.995954,0.001119556,0.001754342,0.0009277661,0.0002069254,0.00003737599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001305367,0.0009805959,6.334307e-7,0.002769895,0.002132277,0.00003048759,0.0001338041,2.691259e-7,0.0008130578,0.001143915,0.002886657,0.987803],"study_design_scores_gemma":[0.0009463259,0.00258198,0.00001886376,0.003181258,0.0006403052,0.0000750281,0.00003333825,4.923045e-8,0.0008177291,0.0004659462,0.9908846,0.0003545617],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001065163,0.9969142,0.00002811392,0.0001611338,0.0006614146,0.0007401526,0.000286295,0.00003157969,0.001070603],"genre_scores_gemma":[0.0002826572,0.996828,0.00006290485,0.0002286814,0.00002033652,0.00006564712,0.0003593779,0.00005738005,0.002095021],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9879979,"threshold_uncertainty_score":0.9999982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.118643813715798,"score_gpt":0.420629290243565,"score_spread":0.301985476527767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}