{"id":"W2108968405","doi":"10.1080/19336950.2015.1092836","title":"Anticonvulsant mechanisms of piperine, a piperidine alkaloid","year":2015,"lang":"en","type":"article","venue":"Channels","topic":"Piperaceae Chemical and Biological Studies","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"","keywords":"Piperine; Strychnine; Picrotoxin; Pharmacology; Pentylenetetrazol; Anticonvulsant; Chemistry; Convulsion; Antagonist; Anesthesia; Epilepsy; Medicine; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007871326,0.0003660111,0.0002982799,0.0002079325,0.00009318591,0.000130269,0.0001710665,0.0002093816,0.0009907538],"category_scores_gemma":[0.0001188429,0.0000985487,0.0002079953,0.00008087049,0.000119588,0.0002464292,0.0001142944,0.000312379,0.000193437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000103539,"about_ca_system_score_gemma":0.00008933018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001894764,"about_ca_topic_score_gemma":0.0003731643,"domain_scores_codex":[0.9999632,0.000007587113,0.000004335488,0.000008091233,0.00001048837,0.000006390068],"domain_scores_gemma":[0.9999268,0.0000129136,0.00003131752,0.000004764295,0.00001247682,0.00001160869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003610968,0.00003841794,0.0002763611,0.00039837,0.00001341902,0.0002181138,0.00002144775,0.0001119519,0.9908587,0.0001083973,0.0000837114,0.007509941],"study_design_scores_gemma":[0.0001002646,0.00377506,0.01264977,0.00006395957,0.000119742,0.002073051,0.00003936986,0.001693817,0.9721025,0.0001656223,0.007199917,0.00001690925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9705201,0.01916272,0.004702522,0.0002334829,0.00005377681,0.0000774008,0.0006085072,0.0002740049,0.004367498],"genre_scores_gemma":[0.9884089,0.007150705,0.002383604,0.0001141451,0.00002326551,0.00002762095,0.0004314559,0.00001316014,0.001447269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009907538,"threshold_uncertainty_score":0.003314376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2644440432291444,"score_gpt":0.4318137006417634,"score_spread":0.167369657412619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}