{"id":"W2109024924","doi":"10.1128/iai.68.8.4485-4491.2000","title":"<i>Salmonella enterica</i> Serovar Typhimurium <i>waaP</i> Mutants Show Increased Susceptibility to Polymyxin and Loss of Virulence In Vivo","year":2000,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Guelph","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Salmonella enterica; Mutant; Virulence; Biology; Microbiology; Polymyxin; Escherichia coli; Heptose; Polymyxin B; Bacterial outer membrane; Salmonella; Enterobacteriaceae; Plasmid; Bacteria; Gene; Genetics; Antibiotics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001604346,0.0007792684,0.0002676877,0.0003214948,0.0001480878,0.000395556,0.0003187028,0.0003868965,0.001231442],"category_scores_gemma":[0.0001739784,0.0002786456,0.0004368958,0.0002166657,0.0003352859,0.0001753061,0.0004402123,0.0006719643,0.0007777946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002608501,"about_ca_system_score_gemma":0.0001790498,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001272399,"about_ca_topic_score_gemma":0.0009472091,"domain_scores_codex":[0.9997194,0.00004205931,0.00005079247,0.00004700422,0.00008120694,0.00005955778],"domain_scores_gemma":[0.999537,0.00004439277,0.0002035847,0.00007069712,0.00004228956,0.0001019834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009623647,0.00003406623,0.0002253145,0.00001774548,0.000009174908,0.00006275738,0.00001004455,0.00005818147,0.9990182,0.00004819518,0.00003025259,0.0003899301],"study_design_scores_gemma":[0.0000203012,0.0005298028,0.008255512,0.00001135203,0.00002557871,0.0006758987,0.00006346478,0.0009308226,0.9879184,0.00004388922,0.001511006,0.00001401305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959097,0.0001876576,0.002208819,0.0000800206,0.00002564429,0.00002313509,0.0006104471,0.0001410496,0.0008135271],"genre_scores_gemma":[0.9929507,0.0001719665,0.002871623,0.00009647485,0.000009624111,0.00003675077,0.001300043,0.0001293113,0.002433503],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001272399,"threshold_uncertainty_score":0.004119575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006240716930038322,"score_gpt":0.237153537826172,"score_spread":0.2309128208961337,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}