{"id":"W2109069233","doi":"10.1073/pnas.0913492107","title":"Gene knockout of Acc2 has little effect on body weight, fat mass, or food intake","year":2010,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":107,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Pyruvate carboxylase; Acetyl-CoA carboxylase; Endocrinology; Internal medicine; Skeletal muscle; Body weight; Obesity; Chemistry; Biology; Biochemistry; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002115569,0.0009036487,0.0006133033,0.0007594628,0.0002282108,0.0004945089,0.0003971516,0.0007116958,0.004300958],"category_scores_gemma":[0.000242497,0.0003690844,0.0003819564,0.0002898982,0.0007714049,0.0003797037,0.0002988307,0.001241785,0.001254032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003204718,"about_ca_system_score_gemma":0.0002892088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007415949,"about_ca_topic_score_gemma":0.001416757,"domain_scores_codex":[0.9997011,0.00003089789,0.00003224956,0.00009580531,0.00008346498,0.00005650061],"domain_scores_gemma":[0.9994154,0.00007422066,0.0001213207,0.00008625288,0.00004030269,0.0002625876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000660548,0.00008984828,0.0004322229,0.00004486555,0.00002219481,0.00009070292,0.00001555669,0.00003533233,0.9965019,0.00007816911,0.0001444615,0.001883989],"study_design_scores_gemma":[0.0001494098,0.001274784,0.01446881,0.00002436453,0.00007892368,0.0007576684,0.00007175277,0.0005682857,0.976508,0.0001355351,0.005941872,0.00002063587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903165,0.001511642,0.002348572,0.0003203757,0.0001806079,0.00004149361,0.002232352,0.0003630902,0.002685562],"genre_scores_gemma":[0.9739072,0.001937166,0.003608632,0.0004388694,0.00006841145,0.0002113704,0.004405426,0.000325347,0.01509754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004300958,"threshold_uncertainty_score":0.01438814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04692172967371997,"score_gpt":0.3212618892133593,"score_spread":0.2743401595396393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}