{"id":"W2109074679","doi":"10.4049/jimmunol.174.11.6764","title":"A Defect in Lineage Fate Decision during Fetal Thymic Invariant NKT Cell Development May Regulate Susceptibility to Type 1 Diabetes","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"National Center for Research Resources; Canadian Institutes of Health Research; Robarts Research Institute; National Institutes of Health","keywords":"CD8; Biology; T cell; Immunology; Fetus; Pathogenesis; Lineage (genetic); Type 1 diabetes; Spleen; T-cell receptor; Natural killer T cell; Embryonic stem cell; Endocrinology; Immune system; Diabetes mellitus; Pregnancy; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001186831,0.0001968095,0.0001360366,0.0002294319,0.0001037539,0.0002892188,0.0001468996,0.0002360334,0.0007981205],"category_scores_gemma":[0.0003172697,0.0001130061,0.00008772716,0.00006744088,0.0002331848,0.0002095482,0.0001691012,0.000397233,0.0001955977],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002103463,"about_ca_system_score_gemma":0.000156055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002906418,"about_ca_topic_score_gemma":0.0003903085,"domain_scores_codex":[0.9999114,0.00001597575,0.0000105483,0.0000196756,0.00001409542,0.00002835068],"domain_scores_gemma":[0.9996936,0.00004654951,0.0001360469,0.00002886667,0.0000218931,0.000072977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002724152,0.00002003522,0.007726795,0.000012443,0.000003114336,0.0002889369,0.00003005326,0.00007313925,0.9892675,0.0001819975,0.00001954772,0.002104017],"study_design_scores_gemma":[0.0000596719,0.0007154372,0.1869578,0.00002719983,0.00005139783,0.005284289,0.0002572947,0.002222387,0.8018148,0.0006227681,0.001969152,0.00001782482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987165,0.0002918041,0.0006080733,0.00002544904,0.000004109614,0.000002030295,0.00004310275,0.00002272513,0.0002861811],"genre_scores_gemma":[0.9989756,0.0002055124,0.0003389179,0.00001356908,0.000003855871,0.000003324375,0.00005847859,0.000006842994,0.0003938889],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007981205,"threshold_uncertainty_score":0.00266993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009514554799550259,"score_gpt":0.2271312734622609,"score_spread":0.2176167186627106,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}