{"id":"W2109087317","doi":"10.1093/hmg/ddp496","title":"Mutation of the bone morphogenetic protein GDF3 causes ocular and skeletal anomalies","year":2009,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Craniofacial Disorders and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":161,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Biology; Bone morphogenetic protein; Mutation; Bone morphogenetic protein 2; Bone morphogenetic protein 7; Genetics; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009701766,0.000575906,0.0002297813,0.0005948909,0.0001967703,0.0001466988,0.0001426949,0.0003247224,0.001001288],"category_scores_gemma":[0.000169157,0.0001704502,0.0002219344,0.0002083425,0.0005039643,0.00007500027,0.0003070107,0.0003413123,0.00019827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003859344,"about_ca_system_score_gemma":0.0003493029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00161331,"about_ca_topic_score_gemma":0.004702004,"domain_scores_codex":[0.9998782,0.0000124224,0.00001212897,0.00002642186,0.00004975245,0.00002114138],"domain_scores_gemma":[0.9999405,0.0000131553,0.00002221732,0.000004860192,0.000003176976,0.00001605817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00008969338,0.00001614441,0.002446876,0.00002422355,0.0000141037,0.001997532,0.0000124954,0.0001039265,0.992309,0.000212663,0.00006176482,0.002711678],"study_design_scores_gemma":[0.000048052,0.0001893816,0.03130173,0.00001273664,0.00008851452,0.02788191,0.00006693761,0.001370959,0.9356188,0.0003017133,0.003102171,0.00001711791],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958577,0.0005500652,0.00219203,0.00009889486,0.00001249911,0.00001749967,0.0003160455,0.00007938025,0.0008758679],"genre_scores_gemma":[0.9964216,0.0004393354,0.002015057,0.00003004136,0.000003677862,0.00001113549,0.0001888929,0.00001906327,0.0008712273],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00161331,"threshold_uncertainty_score":0.003349662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005745532473596357,"score_gpt":0.2341297074070829,"score_spread":0.2283841749334866,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}