{"id":"W2109115818","doi":"10.1021/es503833q","title":"Bioaccumulation, Biotransformation, and Toxicity of BDE-47, 6-OH-BDE-47, and 6-MeO-BDE-47 in Early Life-Stages of Zebrafish (<i>Danio rerio</i>)","year":2015,"lang":"en","type":"article","venue":"Environmental Science & Technology","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"State Administration of Foreign Experts Affairs; Ministry of Science and Technology of the People's Republic of China; Chinese Academy of Sciences; National Natural Science Foundation of China; Canada Research Chairs","keywords":"Polybrominated diphenyl ethers; Bioaccumulation; Diphenyl ether; Aryl hydrocarbon receptor; Chemistry; Estrogen receptor; Biotransformation; Environmental chemistry; Developmental toxicity; Bioconcentration; Toxicity; Internal medicine; Biochemistry; Pollutant; Biology; Gene; Organic chemistry; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.001046315,0.0003055668,0.0004249568,0.0004994411,0.0001806251,0.00003778173,0.0007250876,0.0002859439,0.0002627798],"category_scores_gemma":[0.0002927767,0.0002912027,0.00003803916,0.001560393,0.005994312,0.001290772,0.0006625516,0.0002728581,0.00004883647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004728979,"about_ca_system_score_gemma":0.00006884665,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002585634,"about_ca_topic_score_gemma":0.0001332523,"domain_scores_codex":[0.9970855,0.00006505829,0.0007098248,0.000697734,0.0007812188,0.0006607317],"domain_scores_gemma":[0.9986984,0.00004666772,0.0003372776,0.0005684316,0.00000417308,0.0003450662],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00002560391,0.0001616506,0.3390295,0.000007565706,0.000006845436,0.000003799562,0.001623709,0.00007163858,0.6464724,0.00008634049,0.00003074568,0.01248022],"study_design_scores_gemma":[0.0008614722,0.0004353878,0.6582462,0.00002265753,0.00001341113,0.00003927268,0.001050605,0.0003295213,0.3371933,0.00109213,0.000420536,0.0002955387],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971578,0.0002684222,0.0002790314,0.00100212,0.00008252631,0.0004491395,0.0001111621,0.00007146216,0.0005783748],"genre_scores_gemma":[0.9982693,0.0001941896,0.001323401,0.0001202518,0.00001154141,0.000007304897,0.000001964005,0.00002090918,0.00005111855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3192167,"threshold_uncertainty_score":0.999954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009262328020288613,"score_gpt":0.2221486434606255,"score_spread":0.2128863154403369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}