{"id":"W2109145711","doi":"10.1210/jcem.87.8.8764","title":"Androgen Inactivation in Human Lung Fibroblasts: Variations in Levels of 17β-Hydroxysteroid Dehydrogenase Type 2 and 5α-Reductase Activity Compatible with Androgen Inactivation","year":2002,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Chemical Reactions and Isotopes","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Medical Research Council","keywords":"Dihydrotestosterone; Testosterone (patch); Internal medicine; Endocrinology; Androgen; Androstenedione; Chemistry; Reductase; Biology; Hormone; Biochemistry; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001575019,0.0002482661,0.0001448979,0.0001844118,0.0001236828,0.0002528307,0.00007825022,0.000162018,0.001389753],"category_scores_gemma":[0.0002065497,0.0001218983,0.0001947175,0.0001556987,0.0001382289,0.0001006486,0.00008799233,0.0002358033,0.0005298702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001244144,"about_ca_system_score_gemma":0.0001335377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00101365,"about_ca_topic_score_gemma":0.000822522,"domain_scores_codex":[0.9998592,0.00002877434,0.00001747047,0.00003931421,0.00003272475,0.00002233721],"domain_scores_gemma":[0.9998518,0.00004313291,0.00002448041,0.0000250189,0.00002240309,0.00003317726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001195025,0.00001294022,0.0008216794,0.000009412764,0.000003552711,0.00007258816,0.00002847311,0.00001086473,0.9981703,0.00001159988,0.000007782178,0.0007313055],"study_design_scores_gemma":[0.00001080548,0.0006261569,0.03567592,0.000003008877,0.00002430194,0.0006009218,0.00008216686,0.000199504,0.9612659,0.0000333899,0.001472851,0.000005144418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935821,0.002279158,0.002225147,0.00003073884,0.00002273936,0.00002460231,0.0004494467,0.00004708627,0.001339037],"genre_scores_gemma":[0.9928021,0.00100552,0.001759826,0.00003749675,0.00001072441,0.00003896837,0.001240865,0.00001339814,0.003091134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001389753,"threshold_uncertainty_score":0.004649162,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.170667456052157,"score_gpt":0.4555238820935599,"score_spread":0.2848564260414029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}