{"id":"W2109156325","doi":"10.1093/jac/dkq143","title":"Anti-biofilm and resistance suppression activities of CXA-101 against chronic respiratory infection phenotypes of Pseudomonas aeruginosa strain PAO1","year":2010,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Instituto de Salud Carlos III","keywords":"Pseudomonas aeruginosa; Microbiology; Ciprofloxacin; Biofilm; Ceftazidime; Cystic fibrosis; Biology; Meropenem; Strain (injury); Respiratory tract infections; Antibiotic resistance; Antibiotics; Bacteria; Respiratory system; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002730503,0.0001653395,0.000349863,0.00008939546,0.00005897059,0.00002201402,0.0001049325,0.0002344215,0.00001624424],"category_scores_gemma":[0.00003086909,0.0001429911,0.000143714,0.00007226296,0.0002376817,0.00002400002,0.00003085691,0.0002137545,1.470158e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001136492,"about_ca_system_score_gemma":0.0001570958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001068745,"about_ca_topic_score_gemma":0.00005661502,"domain_scores_codex":[0.9990362,0.0000583149,0.0004531971,0.0001660498,0.0001153171,0.0001709015],"domain_scores_gemma":[0.9989232,0.0000172168,0.0006613597,0.0001868491,0.0001566816,0.00005465475],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005002887,0.0000883075,0.001260392,0.0000912618,0.00007272876,0.000002186331,0.00007429817,0.000007819992,0.99234,0.00001351436,0.001202862,0.004346345],"study_design_scores_gemma":[0.001253553,0.0003079617,0.00512822,0.0001427956,0.00001756964,0.00002582737,0.00001498693,0.000002008174,0.9774453,0.000006324315,0.01551497,0.0001404979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987928,0.0002985369,0.00005119557,0.000190237,0.0004281883,0.00008544529,0.00004200774,0.000003633962,0.0001079261],"genre_scores_gemma":[0.9958331,0.001300501,0.002089664,0.0001823173,0.0005273124,1.996543e-7,0.00001033472,0.00002285904,0.00003372989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01489471,"threshold_uncertainty_score":0.5831008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006134710339868388,"score_gpt":0.2308395072355619,"score_spread":0.2247047968956935,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}