{"id":"W2109252714","doi":"10.1002/bit.22987","title":"Engineered heart tissue enables study of residual undifferentiated embryonic stem cell activity in a cardiac environment","year":2010,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Heart and Stroke Foundation; University Health Network; University of Guelph; Toronto General Hospital; University of Toronto","funders":"National Heart, Lung, and Blood Institute","keywords":"Embryonic stem cell; Population; Cell biology; Progenitor cell; Stem cell; Cell; Biology; Cell culture; In vivo; Chemistry; Pathology; Medicine; Biochemistry; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002632868,0.0003661681,0.00024694,0.0002604334,0.0001085023,0.0003948881,0.0002595641,0.0003536103,0.001263426],"category_scores_gemma":[0.0001418562,0.0001602027,0.0001765919,0.0001250322,0.0002436221,0.0002762438,0.0002997346,0.0005511721,0.0004211321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001342622,"about_ca_system_score_gemma":0.0001915834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000188206,"about_ca_topic_score_gemma":0.000323372,"domain_scores_codex":[0.9998616,0.00001747824,0.00001371785,0.00004070193,0.00004934765,0.00001709987],"domain_scores_gemma":[0.999804,0.00005514636,0.00005356108,0.00003107378,0.00002215294,0.00003419537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001133156,0.000008715123,0.0001538289,0.00002695499,0.000001458478,0.00006049748,0.00001088291,0.0000349091,0.9986725,0.0001492678,0.0000107276,0.0008590169],"study_design_scores_gemma":[0.00000833944,0.0001845418,0.003805201,0.00001433453,0.00001481614,0.0004464992,0.00002439289,0.0008249737,0.9912332,0.0001298429,0.003309594,0.000004201885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9131589,0.003626812,0.07621744,0.00008964185,0.0001070553,0.000127598,0.001137533,0.0003386567,0.005196372],"genre_scores_gemma":[0.9467892,0.002782403,0.04260271,0.00009121564,0.00003615379,0.0001753256,0.001212167,0.0001069713,0.006203944],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001263426,"threshold_uncertainty_score":0.004226625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008769723517569633,"score_gpt":0.2190249164610361,"score_spread":0.2102551929434665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}