{"id":"W2109252714","doi":"10.1002/bit.22987","title":"Engineered heart tissue enables study of residual undifferentiated embryonic stem cell activity in a cardiac environment","year":2010,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Heart and Stroke Foundation; University Health Network; University of Guelph; Toronto General Hospital; University of Toronto","funders":"National Heart, Lung, and Blood Institute","keywords":"Embryonic stem cell; Population; Cell biology; Progenitor cell; Stem cell; Cell; Biology; Cell culture; In vivo; Chemistry; Pathology; Medicine; Biochemistry; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001646398,0.000212566,0.0005064647,0.0003901783,0.00003005474,0.000003997255,0.00006742861,0.0003414624,0.000008635879],"category_scores_gemma":[0.00001177496,0.0001773633,0.00002928203,0.0002265178,0.00009333868,0.00002608274,0.00006253929,0.0006178154,0.000002446685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002663839,"about_ca_system_score_gemma":0.00001778408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004610885,"about_ca_topic_score_gemma":0.00001473995,"domain_scores_codex":[0.9990922,0.00002165007,0.0002009249,0.0002932055,0.0001264177,0.0002656342],"domain_scores_gemma":[0.9995271,0.00003423663,0.00003822955,0.0003110362,0.00001087984,0.00007849692],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002898283,0.0002981218,0.004259135,0.0001373233,0.00006864256,0.00002609283,0.0002045708,0.0002500885,0.9925712,0.00005945874,0.00001342593,0.00208293],"study_design_scores_gemma":[0.001505662,0.001048731,0.0802713,0.00006010693,0.00008603025,0.00002823324,0.0003848174,0.0008306712,0.914102,9.11201e-7,0.00150102,0.0001805338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952939,0.002772576,0.0005474354,0.0004924717,0.000290322,0.0004496905,0.000006251053,0.000142384,0.000004998895],"genre_scores_gemma":[0.9988099,0.0001558014,0.0005430522,0.000001610568,0.00006911912,0.00002452094,0.000004713795,0.00002447683,0.0003667881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07846925,"threshold_uncertainty_score":0.7232664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008769723517569633,"score_gpt":0.2190249164610361,"score_spread":0.2102551929434665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}