{"id":"W2109258684","doi":"10.3390/pharmaceutics2010018","title":"Determination of the Pharmacokinetics and Oral Bioavailability of Salicylamine, a Potent γ-Ketoaldehyde Scavenger, by LC/MS/MS","year":2010,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Heart, Lung, and Blood Institute; National Institute on Aging; American Health Assistance Foundation","keywords":"Bioavailability; Pharmacokinetics; Pharmacology; In vivo; Scavenger; Chemistry; In vitro; Oral administration; Inflammation; Medicine; Biochemistry; Biology; Immunology; Antioxidant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003703868,0.0003731163,0.0003529414,0.0002744528,0.0002330816,0.0003991033,0.0001710779,0.0003549512,0.00160661],"category_scores_gemma":[0.0007507059,0.0002390414,0.0002198678,0.0002342189,0.0002772512,0.0003138839,0.0001224914,0.0005473549,0.0006250464],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003347573,"about_ca_system_score_gemma":0.0004739862,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001860574,"about_ca_topic_score_gemma":0.001690417,"domain_scores_codex":[0.9998066,0.00003430557,0.00001067277,0.00005763629,0.00007069016,0.00002011199],"domain_scores_gemma":[0.9997804,0.00004976666,0.00006868466,0.0000328223,0.00003771676,0.00003072726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004173263,0.0001385559,0.004693589,0.0001240536,0.00008793393,0.0001039309,0.00006909871,0.0003176798,0.9561759,0.0001494244,0.0004784717,0.03348818],"study_design_scores_gemma":[0.0002428684,0.004969455,0.02800682,0.00002387147,0.0002075876,0.0007635597,0.00009550519,0.005929131,0.9529278,0.0002230514,0.006578697,0.00003163138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9634649,0.006574577,0.02359621,0.0002542971,0.00008902064,0.0002947077,0.002263693,0.0003448168,0.003117869],"genre_scores_gemma":[0.981779,0.003034064,0.01020987,0.0001940216,0.0000525368,0.0002386909,0.000847269,0.00009311176,0.003551335],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001860574,"threshold_uncertainty_score":0.00537467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0168537751949541,"score_gpt":0.3025132493400519,"score_spread":0.2856594741450977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}