{"id":"W2109268312","doi":"10.1161/hypertensionaha.113.02083","title":"Interferon Regulatory Factor 9 Protects Against Cardiac Hypertrophy by Targeting Myocardin","year":2013,"lang":"en","type":"article","venue":"Hypertension","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Myocardin; Muscle hypertrophy; Pressure overload; Serum response factor; Fibrosis; Cardiac hypertrophy; Transcription factor; Internal medicine; Endocrinology; Cardiac fibrosis; Heart failure; Medicine; Biology; Cell biology; Cancer research; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002259323,0.0003571825,0.0003110016,0.0002006358,0.0001299384,0.0001880608,0.0002382426,0.0002671879,0.001007283],"category_scores_gemma":[0.00009757611,0.0001098576,0.0002015677,0.00006882336,0.000212101,0.0001701191,0.000141048,0.0007833843,0.0002769098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001102633,"about_ca_system_score_gemma":0.0001333232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001068664,"about_ca_topic_score_gemma":0.0002364125,"domain_scores_codex":[0.9999055,0.00002248229,0.000009257684,0.00001598183,0.00001763464,0.00002914745],"domain_scores_gemma":[0.9999241,0.000011251,0.00002001985,0.00001066393,0.000007142723,0.00002683009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002957953,0.0001031826,0.0001623281,0.00002453079,0.000006145098,0.00003163133,0.000005406903,0.00002875995,0.9968485,0.00006607813,0.00004987235,0.00237779],"study_design_scores_gemma":[0.0002231556,0.002619056,0.006415633,0.00001713009,0.00004879723,0.0003444075,0.00003326324,0.001001655,0.9860773,0.0001784055,0.003031963,0.000009289802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927198,0.001944282,0.003393084,0.0002783875,0.0001078797,0.00003229087,0.0001621539,0.0001526587,0.001209412],"genre_scores_gemma":[0.9953246,0.001056026,0.00190241,0.0001111823,0.00004705276,0.00002550229,0.000282098,0.00001926654,0.001231675],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001007283,"threshold_uncertainty_score":0.003369689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009039236916994563,"score_gpt":0.1934293408401448,"score_spread":0.1843901039231502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}