{"id":"W2109268312","doi":"10.1161/hypertensionaha.113.02083","title":"Interferon Regulatory Factor 9 Protects Against Cardiac Hypertrophy by Targeting Myocardin","year":2013,"lang":"en","type":"article","venue":"Hypertension","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Myocardin; Muscle hypertrophy; Pressure overload; Serum response factor; Fibrosis; Cardiac hypertrophy; Transcription factor; Internal medicine; Endocrinology; Cardiac fibrosis; Heart failure; Medicine; Biology; Cell biology; Cancer research; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009810529,0.0002404257,0.0002312576,0.00003067605,0.0001128863,0.00004110975,0.0001851951,0.0002111167,0.0000298893],"category_scores_gemma":[0.000182839,0.0002123078,0.0001788394,0.00006628044,0.00006961466,0.000009259063,0.0001638115,0.000132468,0.0001360848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002792336,"about_ca_system_score_gemma":0.0000421584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002620611,"about_ca_topic_score_gemma":1.807624e-7,"domain_scores_codex":[0.9986089,0.0001147724,0.0002198029,0.0005061005,0.0002134616,0.0003370028],"domain_scores_gemma":[0.9990556,0.00001323087,0.00007600947,0.0005059952,0.000170357,0.0001788394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003400725,0.00004045159,0.0004586507,0.00001553279,0.000040778,0.000003151324,0.00001418802,0.00001447311,0.8867617,0.000001148482,0.1097371,0.00287877],"study_design_scores_gemma":[0.0003512826,0.0002040897,0.001164709,0.00003836088,0.00001471798,0.000004060638,0.00005563775,0.0001594107,0.9638473,0.00001277021,0.03381706,0.0003306265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995595,0.002633224,0.0001554809,0.0000919998,0.0004209664,0.0004836195,0.00003307688,0.00006363733,0.0005230156],"genre_scores_gemma":[0.997718,0.00005941318,0.0004486463,0.0006770565,0.0003415311,0.00009390703,0.000225911,0.00006117157,0.0003743363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07708554,"threshold_uncertainty_score":0.8657663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009039236916994563,"score_gpt":0.1934293408401448,"score_spread":0.1843901039231502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}