{"id":"W2109340289","doi":"10.1128/mcb.01547-07","title":"Epigenetic Control of the Immune Escape Mechanisms in Malignant Carcinomas","year":2007,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Biology; Epigenetics; Histone; Histone acetyltransferase; RNA polymerase II; Chromatin; Chromatin immunoprecipitation; Histone H3; Transcription (linguistics); Acetylation; Promoter; Cancer research; Cell biology; Molecular biology; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006016279,0.0001502871,0.000201772,0.00006210015,0.0000442382,0.000005287438,0.0001822459,0.0002290512,0.000007288886],"category_scores_gemma":[0.00004741003,0.0001161156,0.0001109591,0.000113216,0.0001356825,0.000001031522,0.0001103791,0.00008731036,0.000001001829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007492443,"about_ca_system_score_gemma":0.00003427303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000726529,"about_ca_topic_score_gemma":0.00006476804,"domain_scores_codex":[0.9988199,0.0001612487,0.0003483139,0.0003060031,0.00007805699,0.0002865001],"domain_scores_gemma":[0.9993992,0.00001676074,0.0001156912,0.0003660389,0.00004998385,0.00005235889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004176745,0.00003332577,0.01468268,0.00000913745,0.00002301984,0.000006371171,0.00002338918,0.00004373471,0.9800057,0.0033715,4.266519e-7,0.00175893],"study_design_scores_gemma":[0.0007155242,0.000241326,0.01737663,0.000007968903,0.00002094162,0.00000368635,0.00003196608,0.00005439946,0.9780291,0.002717779,0.0006651761,0.0001354563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8241924,0.01570538,0.1593559,0.00006157342,0.0001277206,0.0002167466,0.000005735058,0.000002580122,0.0003319716],"genre_scores_gemma":[0.9992079,0.0001357728,0.0004281924,0.00009248198,0.00002756977,0.00000757262,0.00003177998,0.00001714041,0.00005162118],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1750155,"threshold_uncertainty_score":0.4735056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004724087273145701,"score_gpt":0.2117125659487061,"score_spread":0.2069884786755604,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}