{"id":"W2109340289","doi":"10.1128/mcb.01547-07","title":"Epigenetic Control of the Immune Escape Mechanisms in Malignant Carcinomas","year":2007,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Biology; Epigenetics; Histone; Histone acetyltransferase; RNA polymerase II; Chromatin; Chromatin immunoprecipitation; Histone H3; Transcription (linguistics); Acetylation; Promoter; Cancer research; Cell biology; Molecular biology; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001552686,0.0001077288,0.0001324155,0.0001870135,0.0001319309,0.0002521608,0.0001444808,0.0001516825,0.0009513684],"category_scores_gemma":[0.0002563662,0.00009174466,0.00009826746,0.00008654931,0.0002395203,0.0001983612,0.0002154564,0.0002274949,0.00017981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002316212,"about_ca_system_score_gemma":0.0001311582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002655899,"about_ca_topic_score_gemma":0.0004108605,"domain_scores_codex":[0.9999274,0.00001479211,0.000005228492,0.00001438905,0.00002210582,0.00001617256],"domain_scores_gemma":[0.9999092,0.00001787303,0.00002966996,0.00001544619,0.00001412936,0.0000136424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000131967,0.0000211143,0.004621162,0.00003995175,0.00001076873,0.0002991419,0.00007656173,0.0002227441,0.9829111,0.001771465,0.0001037521,0.009790323],"study_design_scores_gemma":[0.0000334007,0.0003641935,0.1063216,0.0000240595,0.00005135513,0.002275317,0.0002109021,0.003269586,0.8745583,0.002742536,0.01013289,0.00001588747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896755,0.003186895,0.004135525,0.0002581674,0.00002560705,0.00001707215,0.000112084,0.00009271249,0.002496508],"genre_scores_gemma":[0.9978574,0.0006011109,0.0005053551,0.00004019154,0.00001049981,0.0000079203,0.00004916722,0.000007413885,0.0009209763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009513684,"threshold_uncertainty_score":0.003182709,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004724087273145701,"score_gpt":0.2117125659487061,"score_spread":0.2069884786755604,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}