{"id":"W2109435088","doi":"10.1016/j.bone.2014.07.037","title":"Development, validation and characterization of a novel mouse model of Adynamic Bone Disease (ABD)","year":2014,"lang":"en","type":"article","venue":"Bone","topic":"Heterotopic Ossification and Related Conditions","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Bone resorption; Medicine; Bone remodeling; Osteoid; Tartrate-resistant acid phosphatase; Bone histomorphometry; Renal osteodystrophy; Resorption; Bone mineral; Bone healing; Bone disease; Pathology; Osteoporosis; Osteoclast; Internal medicine; Kidney disease; Anatomy; Trabecular bone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006847435,0.00005090866,0.0001222238,0.00008346919,0.00002557581,0.000003054722,0.00001556702,0.00004279013,0.00002077427],"category_scores_gemma":[0.00003368041,0.00004583977,0.00002012298,0.0000555574,0.00003470528,0.00004852216,0.000009751106,0.00003864489,0.000003306902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001058636,"about_ca_system_score_gemma":0.00005610016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001485058,"about_ca_topic_score_gemma":4.194065e-7,"domain_scores_codex":[0.9995114,0.000008721469,0.0002381951,0.00009259723,0.00009485159,0.00005427983],"domain_scores_gemma":[0.9996113,0.000007044236,0.0001141104,0.0001265625,0.00006809783,0.00007289796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00003194156,0.000203014,0.0009036211,0.0001212938,0.00001506049,1.25798e-7,0.0002403668,0.00002284122,0.9936364,0.002740601,0.000003550195,0.002081164],"study_design_scores_gemma":[0.005906949,0.0001001631,0.2338247,0.0004054835,0.0002502805,0.00001047086,0.00005168211,0.4983062,0.2593899,0.0001778958,0.001295978,0.0002802832],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9452936,0.000006555641,0.0539586,0.0002489584,0.00001521916,0.0001946245,0.00002854052,0.00001630404,0.0002376061],"genre_scores_gemma":[0.9946105,0.00001908076,0.00280583,0.00006333985,0.00001063941,0.00001756282,0.0002885139,0.00000717764,0.002177367],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7342466,"threshold_uncertainty_score":0.1869292,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0266182948862459,"score_gpt":0.2570766466478781,"score_spread":0.2304583517616322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}