{"id":"W2109435088","doi":"10.1016/j.bone.2014.07.037","title":"Development, validation and characterization of a novel mouse model of Adynamic Bone Disease (ABD)","year":2014,"lang":"en","type":"article","venue":"Bone","topic":"Heterotopic Ossification and Related Conditions","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Bone resorption; Medicine; Bone remodeling; Osteoid; Tartrate-resistant acid phosphatase; Bone histomorphometry; Renal osteodystrophy; Resorption; Bone mineral; Bone healing; Bone disease; Pathology; Osteoporosis; Osteoclast; Internal medicine; Kidney disease; Anatomy; Trabecular bone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002365297,0.001679392,0.0007016322,0.004170464,0.0009979683,0.001458258,0.00172298,0.001782259,0.002913191],"category_scores_gemma":[0.0009747536,0.0008244318,0.001161485,0.0007424194,0.001322269,0.001466116,0.0007565367,0.003191747,0.001518812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008432222,"about_ca_system_score_gemma":0.0008046446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001531039,"about_ca_topic_score_gemma":0.002829195,"domain_scores_codex":[0.9982279,0.0002986169,0.0003122594,0.0003894923,0.0004932642,0.000278525],"domain_scores_gemma":[0.998237,0.0003050974,0.0004679603,0.000335021,0.0003090095,0.000345903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000300729,0.0005649302,0.000776538,0.000118866,0.00002809998,0.0002493264,0.0001227447,0.0002308125,0.9916301,0.001964715,0.0003839039,0.003629206],"study_design_scores_gemma":[0.0002829306,0.002106959,0.004792384,0.0001113842,0.0002095723,0.001911131,0.0002473487,0.002873384,0.965905,0.0006255861,0.02089475,0.00003957198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8569069,0.006289472,0.1154976,0.001965566,0.0006406625,0.002106872,0.008197336,0.001141979,0.007253543],"genre_scores_gemma":[0.8538567,0.006790282,0.09351872,0.0008030927,0.0001566381,0.003315888,0.0120722,0.0006027734,0.0288836],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004170464,"threshold_uncertainty_score":0.01250899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0266182948862459,"score_gpt":0.2570766466478781,"score_spread":0.2304583517616322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}