{"id":"W2109475403","doi":"10.1158/0008.5472.can-04-2781","title":"Cyclooxygenase-2 Functions as a Downstream Mediator of Lysophosphatidic Acid to Promote Aggressive Behavior in Ovarian Carcinoma Cells","year":2005,"lang":"en","type":"article","venue":"Cancer Research","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute","keywords":"Lysophosphatidic acid; Ovarian cancer; Cancer research; Metastasis; Ovarian carcinoma; Biology; Amphiregulin; Transactivation; Internal medicine; Epidermal growth factor receptor; Cancer; Endocrinology; Medicine; Receptor; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004798056,0.0001440681,0.0002060082,0.0002311021,0.00009341639,0.00002205537,0.0003122441,0.0001478553,0.0002018994],"category_scores_gemma":[0.0001874687,0.0001375279,0.00007857366,0.0004816939,0.0001049583,0.000008048169,0.0001680401,0.0002264303,0.00005660031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007003839,"about_ca_system_score_gemma":0.0005373198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008883232,"about_ca_topic_score_gemma":0.0004383239,"domain_scores_codex":[0.9982695,0.000108384,0.0002768208,0.0004457452,0.0003998625,0.0004996757],"domain_scores_gemma":[0.9989471,0.00001600235,0.00008131534,0.0004311177,0.000274239,0.0002501953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001952068,0.0002678903,0.002886067,0.00002194541,0.00001795946,0.00002214864,0.0003514444,0.00005081527,0.9877434,0.00001649749,0.001234223,0.007192377],"study_design_scores_gemma":[0.001395941,0.0002108653,0.003825376,0.00004121119,0.00001536713,0.000006274986,0.0001905694,0.000007223879,0.980938,0.000007604801,0.01322148,0.0001401531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934629,0.005067089,0.00003387024,0.0002518751,0.0002102203,0.0005948942,0.0001007725,0.00000589075,0.0002724638],"genre_scores_gemma":[0.997117,0.0004138271,0.0003420927,0.00008832386,0.0007563772,0.0005770421,0.00004090075,0.00002921786,0.0006352509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01198726,"threshold_uncertainty_score":0.5608227,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02349917448408743,"score_gpt":0.3391048644650601,"score_spread":0.3156056899809727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}