{"id":"W2109488064","doi":"10.1016/j.it.2004.04.009","title":"Cornerstone of peripheral tolerance: naturally occurring CD4+CD25+ regulatory T cells","year":2004,"lang":"en","type":"review","venue":"Trends in Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":168,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"","keywords":"Cornerstone; IL-2 receptor; Peripheral tolerance; Immunology; Immune tolerance; Regulatory T cell; Biology; Immunity; Treg cell; T cell; Population; Antigen; Medicine; Immune system; Geography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001197618,0.001138099,0.001977108,0.0007789581,0.0003609579,0.001503764,0.001559125,0.002381805,0.002368381],"category_scores_gemma":[0.0007964984,0.0002907488,0.0003483084,0.0006894785,0.00115763,0.002434389,0.0007157609,0.004334127,0.002553909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007739478,"about_ca_system_score_gemma":0.001079159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003997523,"about_ca_topic_score_gemma":0.0005126291,"domain_scores_codex":[0.9997538,0.00004132306,0.00002793862,0.00005651711,0.00008986647,0.00003061063],"domain_scores_gemma":[0.9996356,0.0001268998,0.00003792603,0.00001569985,0.0001109759,0.00007302289],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003288682,0.00008494315,0.0002174667,0.005096095,0.0000445947,0.0004976622,0.00005189109,0.000392609,0.008826824,0.007209824,0.06073191,0.9165173],"study_design_scores_gemma":[0.00008962779,0.0002652822,0.0006352899,0.001265314,0.00008470103,0.002314643,0.00006376707,0.0001952226,0.002897784,0.006850585,0.9853119,0.00002587975],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003842214,0.9909046,0.001530652,0.002789694,0.002845435,0.00001073306,0.00001964029,0.00005402333,0.00146097],"genre_scores_gemma":[0.004708885,0.9820756,0.001572812,0.004588021,0.004175933,0.00003090273,0.00007055453,0.00001006485,0.002767164],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002381805,"threshold_uncertainty_score":0.007923067,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02217424371619115,"score_gpt":0.2839762706958538,"score_spread":0.2618020269796626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}