{"id":"W2109565914","doi":"10.1128/mbio.01112-15","title":"Function of the CRISPR-Cas System of the Human Pathogen Clostridium difficile","year":2015,"lang":"en","type":"article","venue":"mBio","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of General Medical Sciences; Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Université Paris Diderot; Agence Nationale de la Recherche","keywords":"CRISPR; Clostridium difficile; Biology; Plasmid; Microbiology; Computational biology; Bacteriophage; Genetics; DNA; Gene; Escherichia coli; Antibiotics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000298479,0.000616408,0.0002455352,0.0002694571,0.0003241972,0.0007234081,0.0004311563,0.0007290005,0.003391823],"category_scores_gemma":[0.000405345,0.00009997835,0.0002155002,0.0001825392,0.000486908,0.0002249206,0.0002983359,0.0005148155,0.00127769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006183936,"about_ca_system_score_gemma":0.0005966042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001187921,"about_ca_topic_score_gemma":0.0006955356,"domain_scores_codex":[0.9996412,0.0000598332,0.00003009056,0.000111379,0.0001037391,0.0000536977],"domain_scores_gemma":[0.9996949,0.00007579695,0.00006563878,0.00003579845,0.0000690122,0.00005879312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007112993,0.000077366,0.00390683,0.00120124,0.00004346566,0.0004231233,0.00009844377,0.001410213,0.8961581,0.002921201,0.00282268,0.09022601],"study_design_scores_gemma":[0.00005282375,0.0007129092,0.01328607,0.0001522084,0.00008994179,0.002574898,0.0001187302,0.004926593,0.9084281,0.001168236,0.06843819,0.00005113729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7258764,0.09480135,0.1029761,0.004280877,0.001652952,0.0004053105,0.005115342,0.00527035,0.05962138],"genre_scores_gemma":[0.9649792,0.005848296,0.02152312,0.0003790194,0.00008255099,0.00004884999,0.001401781,0.0000810825,0.005656052],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003391823,"threshold_uncertainty_score":0.01134682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04323370947235679,"score_gpt":0.2931125118537284,"score_spread":0.2498788023813716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}