{"id":"W2109565914","doi":"10.1128/mbio.01112-15","title":"Function of the CRISPR-Cas System of the Human Pathogen Clostridium difficile","year":2015,"lang":"en","type":"article","venue":"mBio","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of General Medical Sciences; Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Université Paris Diderot; Agence Nationale de la Recherche","keywords":"CRISPR; Clostridium difficile; Biology; Plasmid; Microbiology; Computational biology; Bacteriophage; Genetics; DNA; Gene; Escherichia coli; Antibiotics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004754866,0.0001762449,0.00037606,0.00007785856,0.0001403408,0.00001271309,0.0003759344,0.0001495729,0.00006791424],"category_scores_gemma":[0.0002244135,0.00009748614,0.0003067782,0.0005858561,0.0002325263,0.00003042808,0.0002718704,0.0003375021,0.00003315584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002493987,"about_ca_system_score_gemma":0.0003470182,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003864933,"about_ca_topic_score_gemma":0.0000345341,"domain_scores_codex":[0.9978405,0.0001583446,0.000498569,0.000253464,0.0009389294,0.0003101956],"domain_scores_gemma":[0.9980952,0.00005326635,0.0002307985,0.001036818,0.0004377849,0.0001461063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002785523,0.0004124867,0.0186269,0.000458901,0.0001147547,0.000008248543,0.0004413046,0.00001917293,0.9632994,0.001353106,0.01415699,0.0008302041],"study_design_scores_gemma":[0.001708422,0.0004539596,0.02285623,0.0002944381,0.0002429804,0.0000383488,0.001578197,0.00009402683,0.9650565,0.00003717296,0.007520357,0.0001193101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873399,0.0004126849,0.00002056161,0.0007764668,0.0005918217,0.0006831012,0.00009730105,0.00003884982,0.01003937],"genre_scores_gemma":[0.9976236,0.000007157401,0.000008405171,0.00004875552,0.0002819477,0.0000187704,0.00001680786,0.00002767173,0.001966923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01028372,"threshold_uncertainty_score":0.3975369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04323370947235679,"score_gpt":0.2931125118537284,"score_spread":0.2498788023813716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}