{"id":"W2109646193","doi":"10.1152/ajpgi.00058.2013","title":"Kupffer cells and activation of endothelial TLR4 coordinate neutrophil adhesion within liver sinusoids during endotoxemia","year":2013,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Intravital microscopy; Endothelium; Biology; TLR4; Inflammation; Innate immune system; Immunology; Endothelial activation; Endothelial stem cell; Pathology; Cell biology; Medicine; Immune system; In vivo; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001958287,0.0003052109,0.0007734646,0.0002436772,0.0001608797,0.00001085561,0.0002040554,0.0001013057,0.0001808842],"category_scores_gemma":[0.0001015417,0.0002370482,0.0001400265,0.0001371107,0.00134566,0.0003450051,0.0001492591,0.0005377678,0.00004004853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003279782,"about_ca_system_score_gemma":0.00007132466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003911062,"about_ca_topic_score_gemma":0.000001280648,"domain_scores_codex":[0.9979283,0.0006123022,0.0006990714,0.0003115942,0.00005745452,0.0003912796],"domain_scores_gemma":[0.9977952,0.0004307021,0.001192451,0.0001828805,0.0003358126,0.00006291017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002239832,0.0001121036,0.0004346584,0.00006527293,0.0001178011,0.00000637839,0.0004803383,0.00005132144,0.9935036,0.000195657,0.00009949162,0.002693544],"study_design_scores_gemma":[0.001504054,0.00398882,0.2363721,0.0002074439,0.00006354797,0.001286656,0.0005831546,0.00007407599,0.7552878,0.0003586777,0.00007801761,0.0001956521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991366,0.0003163497,0.00004346826,0.0000991233,0.0001557781,0.0001938766,0.000007604368,0.00001642411,0.00003077043],"genre_scores_gemma":[0.9985287,0.0003034348,0.0007713501,0.00008733277,0.0001234841,0.000008661407,0.00001265902,0.00002043357,0.0001439342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2382157,"threshold_uncertainty_score":0.9666543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005183405817157078,"score_gpt":0.1896563826955621,"score_spread":0.1844729768784051,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}