{"id":"W2109646193","doi":"10.1152/ajpgi.00058.2013","title":"Kupffer cells and activation of endothelial TLR4 coordinate neutrophil adhesion within liver sinusoids during endotoxemia","year":2013,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Intravital microscopy; Endothelium; Biology; TLR4; Inflammation; Innate immune system; Immunology; Endothelial activation; Endothelial stem cell; Pathology; Cell biology; Medicine; Immune system; In vivo; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002229238,0.0002399397,0.0002812269,0.0002499843,0.0001490907,0.0002907859,0.00009676478,0.0002448958,0.0007378742],"category_scores_gemma":[0.0002108939,0.0001590377,0.0002207703,0.00009665982,0.0002324079,0.0002265177,0.0003573648,0.0006028865,0.00026601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003070526,"about_ca_system_score_gemma":0.0001846389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003755934,"about_ca_topic_score_gemma":0.000434898,"domain_scores_codex":[0.9997494,0.00006251642,0.00002200598,0.00003751148,0.00005518407,0.00007340989],"domain_scores_gemma":[0.9998024,0.00001524591,0.00007886724,0.0000207017,0.00002695115,0.00005584498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002694789,0.0000133398,0.0005728223,0.00002802889,0.000003750825,0.000142672,0.00005694337,0.00002997295,0.9980349,0.000132964,0.00002977608,0.0006851919],"study_design_scores_gemma":[0.00005853761,0.0004339748,0.05527183,0.00001885523,0.00004357001,0.0007370893,0.0003458545,0.002520452,0.9377867,0.0002362015,0.002534041,0.0000127486],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963388,0.0007652811,0.002011663,0.00006579044,0.00001465038,0.00001957179,0.00006745809,0.00003440805,0.0006823713],"genre_scores_gemma":[0.9958616,0.0004541037,0.001868316,0.00004607212,0.00001649682,0.00005778089,0.0001241367,0.00001003149,0.001561587],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007378742,"threshold_uncertainty_score":0.002468467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005183405817157078,"score_gpt":0.1896563826955621,"score_spread":0.1844729768784051,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}