{"id":"W2109674742","doi":"10.1158/0008-5472.can-05-1341","title":"Hypoxia Increases Androgen Receptor Activity in Prostate Cancer Cells","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute","keywords":"Androgen receptor; Prostate cancer; DU145; LNCaP; Androgen; Hypoxia (environmental); Endocrinology; Internal medicine; Enzalutamide; Cancer research; Androgen deprivation therapy; Tumor hypoxia; Biology; Chemistry; Medicine; Cancer; Hormone; Oxygen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008754607,0.0002307389,0.0003291166,0.0001901444,0.0001838822,0.0003186417,0.0001361586,0.0001489298,0.003351366],"category_scores_gemma":[0.00009545431,0.0001159318,0.0002747827,0.000269619,0.00008835624,0.0001237218,0.0002129889,0.0003875799,0.0008474075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003041101,"about_ca_system_score_gemma":0.0002540033,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002646162,"about_ca_topic_score_gemma":0.002948783,"domain_scores_codex":[0.9998223,0.00002899759,0.00001287015,0.00003588963,0.00006511665,0.00003481995],"domain_scores_gemma":[0.9999298,0.00001306494,0.00001302254,0.000007341056,0.00001357461,0.0000232557],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001302793,0.00006064739,0.0003240228,0.0001340849,0.0000108477,0.00008262641,0.00003699823,0.0000619152,0.9948872,0.0001117582,0.0005216543,0.003638208],"study_design_scores_gemma":[0.00004678021,0.001789275,0.04708054,0.00003409788,0.00005714646,0.001040385,0.0001084722,0.001326644,0.8975068,0.0001402651,0.05084708,0.00002258444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9334547,0.03877975,0.006406979,0.0007705195,0.0003970508,0.0001440838,0.003654868,0.000446826,0.01594527],"genre_scores_gemma":[0.9689733,0.00926463,0.002551484,0.0004179946,0.0001303488,0.0001052326,0.004428175,0.00004319248,0.01408578],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003351366,"threshold_uncertainty_score":0.0112114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02621021387007108,"score_gpt":0.3391583134548568,"score_spread":0.3129480995847857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}