{"id":"W2109674742","doi":"10.1158/0008-5472.can-05-1341","title":"Hypoxia Increases Androgen Receptor Activity in Prostate Cancer Cells","year":2006,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute","keywords":"Androgen receptor; Prostate cancer; DU145; LNCaP; Androgen; Hypoxia (environmental); Endocrinology; Internal medicine; Enzalutamide; Cancer research; Androgen deprivation therapy; Tumor hypoxia; Biology; Chemistry; Medicine; Cancer; Hormone; Oxygen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005394014,0.000178122,0.0002207305,0.0001449499,0.0001244888,0.00005092331,0.0002682293,0.0001390058,0.0002373883],"category_scores_gemma":[0.00004367337,0.0001728366,0.00007722307,0.000405708,0.0002094782,0.0000115416,0.0001790327,0.0002984635,0.00002486104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001492759,"about_ca_system_score_gemma":0.0007176014,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0258208,"about_ca_topic_score_gemma":0.01112908,"domain_scores_codex":[0.9979331,0.0002235461,0.0001876733,0.0005700004,0.0003780806,0.0007076244],"domain_scores_gemma":[0.9991767,0.00002712539,0.00005312096,0.0003844867,0.0002186227,0.0001399686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004010938,0.0001239411,0.004198688,0.00004354527,0.00002093807,0.000002796983,0.00003304139,0.0001160616,0.9366189,0.00001557206,0.0459728,0.01245257],"study_design_scores_gemma":[0.0006781872,0.00005263288,0.006110681,0.00002832828,0.000005120262,0.000001272689,0.00002436015,0.000005814941,0.6289635,0.00004403936,0.3639261,0.0001600382],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.977739,0.01976004,0.000004916971,0.0002802222,0.0005534912,0.0005027558,0.0002733692,0.00001376493,0.0008724568],"genre_scores_gemma":[0.9729614,0.01650786,0.00005192175,0.00008220128,0.002678445,0.000710058,0.0000573446,0.00004571611,0.006905069],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3179532,"threshold_uncertainty_score":0.9806663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02621021387007108,"score_gpt":0.3391583134548568,"score_spread":0.3129480995847857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}