{"id":"W2109702138","doi":"10.1139/v09-030","title":"8-Isocyanoamphilecta-11(20),15-diene, a new antimalarial isonitrile diterpene from the sponge <i>Ciocalapata</i> sp.","year":2009,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Marine Sponges and Natural Products","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Diterpene; Stereochemistry; Plasmodium falciparum; Sponge; Diene; Cytotoxicity; In vitro; Biochemistry; Organic chemistry; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006168053,0.000440688,0.0001855183,0.0004577865,0.0001346046,0.0001828642,0.0001470619,0.0001789723,0.000967951],"category_scores_gemma":[0.00007599957,0.00009782617,0.0001576078,0.0002332332,0.000164486,0.0002366452,0.0002236928,0.0002930902,0.0002224747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001762806,"about_ca_system_score_gemma":0.0002577468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006839253,"about_ca_topic_score_gemma":0.00142849,"domain_scores_codex":[0.9999499,0.000006231272,0.000004437053,0.000008801273,0.00001955648,0.00001103754],"domain_scores_gemma":[0.9999582,0.000003322434,0.000008727624,0.000002770898,0.00001155969,0.00001553175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007040533,0.00001088011,0.0003945837,0.0001291985,0.000005689286,0.0001673391,0.00001824091,0.00007069531,0.9924541,0.00007415216,0.00005170039,0.006553086],"study_design_scores_gemma":[0.00003387318,0.0007603904,0.0181896,0.00003190179,0.00004420242,0.002717998,0.00008539658,0.0003909802,0.9498828,0.0001091789,0.02772761,0.00002609799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9679231,0.01871677,0.004094217,0.0002386215,0.00006816308,0.0001002731,0.001189186,0.00009943203,0.007570232],"genre_scores_gemma":[0.9834139,0.006393169,0.003634144,0.0001545416,0.00002655436,0.0000487934,0.001624918,0.0000099764,0.004693938],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000967951,"threshold_uncertainty_score":0.003238142,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005720679830744379,"score_gpt":0.2010167721747088,"score_spread":0.1952960923439645,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}