{"id":"W2109710025","doi":"10.1016/j.febslet.2014.02.009","title":"Autotaxin in the crosshairs: Taking aim at cancer and other inflammatory conditions","year":2014,"lang":"en","type":"review","venue":"FEBS Letters","topic":"Sphingolipid Metabolism and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Autotaxin; Cancer research; Cancer; Biology; Cancer cell; Angiogenesis; Lysophosphatidylcholine; Signal transduction; Metastasis; Medicine; Cell biology; Pharmacology; Lysophosphatidic acid; Receptor; Internal medicine; Biochemistry; Phospholipid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003376902,0.0002667013,0.0004777214,0.00007017892,0.0001051814,0.00006129847,0.0002683695,0.0002159158,0.00003828804],"category_scores_gemma":[0.00004764642,0.0001898684,0.0001804276,0.00007797709,0.0001261804,0.000002975148,0.0001041471,0.0002085194,0.00001325758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002638728,"about_ca_system_score_gemma":0.00006138271,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000079243,"about_ca_topic_score_gemma":0.0001398279,"domain_scores_codex":[0.9987806,0.0001753129,0.0003081596,0.0003620873,0.0001118037,0.000262057],"domain_scores_gemma":[0.9992942,0.00004566086,0.000260877,0.0003490339,0.00001071265,0.00003952805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001037117,0.0001791862,0.007906947,0.03541543,0.00190316,0.000181065,0.003813242,0.0006057968,0.0723303,0.002032976,0.1847405,0.6907877],"study_design_scores_gemma":[0.0001885102,0.000006413857,0.0001335682,0.0010645,0.0001100853,0.00002743348,0.00001058376,0.000003505538,0.00005102661,0.000002705776,0.9981641,0.0002375445],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02581424,0.9730274,0.00004178252,0.0001815923,0.0002761901,0.0003424882,0.00008466515,0.00001012742,0.0002215081],"genre_scores_gemma":[0.001839856,0.9885734,0.00003150231,0.007361005,0.001448193,0.0003153751,0.0001567638,0.00006548498,0.0002083787],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8134237,"threshold_uncertainty_score":0.7742611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02654432546253764,"score_gpt":0.3238489382883832,"score_spread":0.2973046128258455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}