{"id":"W2109877846","doi":"10.1002/cbic.201500494","title":"Derivatisable Cyanobactin Analogues: A Semisynthetic Approach","year":2015,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; Directorate for Biological Sciences; Sichuan University; Wellcome Trust","keywords":"Combinatorial chemistry; Chemistry; Cyclic peptide; Dehydroalanine; Enzyme; Biochemistry; Computational biology; Peptide; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001590415,0.0003603538,0.0002230373,0.0001233636,0.0000933858,0.0002663549,0.0001898805,0.0003422982,0.0007714402],"category_scores_gemma":[0.0001997415,0.0001245253,0.0001598692,0.000170563,0.0001945815,0.000248809,0.0002393267,0.0006523808,0.0004093592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002704727,"about_ca_system_score_gemma":0.000310665,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003405829,"about_ca_topic_score_gemma":0.0005075412,"domain_scores_codex":[0.9998738,0.00002501666,0.00001488165,0.0000283854,0.00003599322,0.00002197365],"domain_scores_gemma":[0.9999081,0.0000169026,0.00003084941,0.00001638151,0.00001473894,0.00001290874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002097668,0.00001097136,0.00003260382,0.00003125439,0.000002239364,0.00005212442,0.000009908249,0.00008608719,0.9977324,0.0001832047,0.00001990468,0.001818351],"study_design_scores_gemma":[0.000008104854,0.0001411443,0.0002033033,0.000004291273,0.000005266354,0.000194587,0.000007295172,0.000211487,0.9954602,0.00006442342,0.003695265,0.000004718268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.896429,0.005708043,0.08681434,0.0003715557,0.0001901359,0.0003879559,0.0008015927,0.0002662729,0.009031108],"genre_scores_gemma":[0.9409946,0.003795249,0.04967621,0.0001738101,0.00002409576,0.000110783,0.000792133,0.00007893842,0.004354244],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007714402,"threshold_uncertainty_score":0.002580702,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04335678381624253,"score_gpt":0.256214182473989,"score_spread":0.2128573986577465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}