{"id":"W2109943001","doi":"10.1136/ebmed.2011.100206","title":"Tiotropium is superior to salmeterol in reducing frequency of exacerbations: but the effect of adding tiotropium to the combination of inhaled corticosteroid and long-acting β(2)-agonist remains unclear","year":2011,"lang":"en","type":"letter","venue":"Evidence-Based Medicine","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Salmeterol; COPD; Medicine; Tiotropium bromide; Agonist; Inhaled corticosteroids; Corticosteroid; Pulmonary disease; Anesthesia; Internal medicine; Pharmacology; Lung function; Lung; Receptor; Asthma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"not_applicable","genre":"commentary","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"randomized_trial","genre":"commentary","about_ca_system":false,"about_ca_topic":false,"confidence":"medium","status":"direct model label, unvalidated"}],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001890212,0.0004879301,0.001377159,0.0007856797,0.0001411069,0.00001970679,0.0005305182,0.0003114944,0.0003125471],"category_scores_gemma":[0.006544618,0.0003041322,0.0001945968,0.001008303,0.0008307459,0.0001819668,0.0001935535,0.00135818,0.000007662524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000746336,"about_ca_system_score_gemma":0.0005770434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003145828,"about_ca_topic_score_gemma":0.0001137985,"domain_scores_codex":[0.9947698,0.0009931365,0.001419205,0.0007306212,0.00152149,0.0005658023],"domain_scores_gemma":[0.9940572,0.003067987,0.0007041335,0.001265289,0.0006908536,0.0002145767],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01147659,0.0007979095,0.3428298,0.07093324,0.00175659,0.002404144,0.02082116,0.0003062323,0.3266733,0.0001264111,0.1584045,0.06347013],"study_design_scores_gemma":[0.01745042,0.02534045,0.6828598,0.1330104,0.004036487,0.0004492762,0.002354402,0.002262072,0.1233819,0.00009774572,0.007256148,0.001500823],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7526708,0.004888017,0.0003435885,0.2366747,0.0004387657,0.004671773,0.00009136031,0.00002627084,0.0001947058],"genre_scores_gemma":[0.9808276,0.0002976004,0.0002968186,0.01667197,0.00108507,0.0003090373,0.00009776316,0.0000977354,0.0003163633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.34003,"threshold_uncertainty_score":0.9999411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03980680684330738,"score_gpt":0.3119390965725959,"score_spread":0.2721322897292885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}