{"id":"W2109975664","doi":"10.1242/bio.20149407","title":"An investigation of nutrient-dependent mRNA translation in <i>Drosophila</i> larvae","year":2014,"lang":"en","type":"article","venue":"Biology Open","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Cancer Foundation","keywords":"Biology; Anabolism; Translation (biology); P70-S6 Kinase 1; Protein biosynthesis; Polysome; Cell biology; Kinase; PI3K/AKT/mTOR pathway; Messenger RNA; Translational regulation; Catabolism; Nutrient sensing; Metabolism; Signal transduction; Biochemistry; Gene; Ribosome; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006427246,0.000102468,0.0002289132,0.0001174773,0.00008281078,0.00001335909,0.0007462364,0.0001791061,0.00004622904],"category_scores_gemma":[0.0001878997,0.00008885514,0.00002550131,0.0002160917,0.0004308383,0.0002832215,0.0001119468,0.0002217104,0.00004078548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000928482,"about_ca_system_score_gemma":0.0000530583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009851551,"about_ca_topic_score_gemma":0.00004865484,"domain_scores_codex":[0.9976906,0.001291957,0.0002728215,0.0004422771,0.00005531051,0.0002470276],"domain_scores_gemma":[0.9991559,0.0003710427,0.0001011777,0.0002865423,0.0000249428,0.00006036071],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001452806,0.00007140347,0.02293142,0.00000571966,0.000001436366,0.000001003354,0.0001336102,0.00001537992,0.9652686,0.01070858,0.00002155703,0.0006959731],"study_design_scores_gemma":[0.001015224,0.0007880378,0.02911595,0.000009021944,0.000002542629,0.000006813179,0.000009165644,0.000411688,0.9366128,0.03160413,0.0003154495,0.0001091673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973747,0.00001390785,0.00003880316,0.0004636545,0.00014052,0.0004407919,0.00001739433,0.00001912388,0.001491167],"genre_scores_gemma":[0.9987501,0.00003342781,0.00008379913,0.0009747185,0.00004016673,0.00004331058,0.00003258761,0.000008264983,0.00003363921],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02865582,"threshold_uncertainty_score":0.3623407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06823544609360643,"score_gpt":0.3359102281469083,"score_spread":0.2676747820533019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}