{"id":"W2110067577","doi":"10.1016/s1476-5586(03)80022-2","title":"Detection of Hypoxia in Human Brain Tumor Xenografts Using a Modified Comet Assay","year":2003,"lang":"en","type":"article","venue":"Neoplasia","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute; Medical Research Council; University of British Columbia","keywords":"Comet assay; Hypoxia (environmental); Comet; Pathology; In vitro; Tumor hypoxia; Molecular biology; Biology; Chemistry; Cancer research; Medicine; Radiation therapy; Oxygen; DNA damage; Internal medicine; Biochemistry; DNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003199307,0.0001390667,0.0002095258,0.0001173658,0.00005403245,0.00001171578,0.00009421862,0.0001251357,0.00001594388],"category_scores_gemma":[0.0001392705,0.0001496961,0.00008806492,0.0002040035,0.00005523655,0.000004577958,0.00002718016,0.0001020106,0.000001523587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001771304,"about_ca_system_score_gemma":0.00007751022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001531366,"about_ca_topic_score_gemma":0.000572098,"domain_scores_codex":[0.998991,0.000138532,0.0002503865,0.0002651493,0.0001181361,0.0002367925],"domain_scores_gemma":[0.9995083,0.00001423473,0.0001087264,0.000259544,0.00004848057,0.00006076699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003947756,0.00005858481,0.0007142072,0.00001763436,0.00001712848,0.00000143723,0.00005213526,0.0002272807,0.997251,0.0001305856,0.0002535059,0.001236996],"study_design_scores_gemma":[0.001609785,0.0001544964,0.007644557,0.00002025441,0.0000250077,0.0000607273,0.00009788952,0.0001779278,0.934113,0.0001540963,0.05570357,0.0002386737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948726,0.0008053836,0.001819568,0.00001053959,0.0005860546,0.0001663124,0.00001028684,0.000008700033,0.001720592],"genre_scores_gemma":[0.9988567,0.00002850567,0.0004649685,0.0001143605,0.0002743486,0.00001270345,0.00001523605,0.00002191774,0.0002112615],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06313802,"threshold_uncertainty_score":0.6104428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01549896620344452,"score_gpt":0.2621801502749052,"score_spread":0.2466811840714606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}