{"id":"W2110098472","doi":"10.1091/mbc.e05-08-0742","title":"A Critical Role for Eukaryotic Elongation Factor 1A-1 in Lipotoxic Cell Death","year":2005,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Heart and Stroke Foundation of Canada","keywords":"Biology; Lipotoxicity; Cell biology; Programmed cell death; Unfolded protein response; Endoplasmic reticulum; Apoptosis; Endocrinology; Biochemistry; Insulin resistance; Insulin","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002338953,0.0004835009,0.0002484193,0.0002605665,0.0003475258,0.0004754773,0.0001870617,0.0004781792,0.000639721],"category_scores_gemma":[0.0001495836,0.0001107416,0.000245994,0.0001127928,0.0002954973,0.0003128066,0.0002436265,0.0004049736,0.0002790297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005128432,"about_ca_system_score_gemma":0.000249744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003485129,"about_ca_topic_score_gemma":0.000395601,"domain_scores_codex":[0.9999144,0.00001302217,0.000009259708,0.00002443611,0.00001652445,0.00002226253],"domain_scores_gemma":[0.9998724,0.00001845954,0.00003971941,0.00001434306,0.00001916058,0.00003590027],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006571944,0.00004991091,0.001507197,0.0001611534,0.00001534786,0.0005747513,0.00003536751,0.0001959424,0.9885587,0.0009336238,0.0002816305,0.007029236],"study_design_scores_gemma":[0.0001054423,0.0007930928,0.05723323,0.00009632518,0.00007831442,0.003050572,0.0001441783,0.001831923,0.9153284,0.001553226,0.01975576,0.00002950412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9168292,0.06893923,0.007822048,0.001496328,0.0003169132,0.00005185239,0.0007893312,0.0001914108,0.003563686],"genre_scores_gemma":[0.9859201,0.009471964,0.001760015,0.0001770374,0.00005683002,0.00003411781,0.0006105793,0.000009688501,0.001959668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000639721,"threshold_uncertainty_score":0.003720939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006023603115097596,"score_gpt":0.258086526848688,"score_spread":0.2520629237335904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}