{"id":"W2110141337","doi":"10.1128/iai.01217-07","title":"Toll-Like Receptor 9-Dependent Macrophage Activation by <i>Entamoeba histolytica</i> DNA","year":2007,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Amoebic Infections and Treatments","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Association of Gastroenterology; McGill University","keywords":"Entamoeba histolytica; Biology; TLR9; Toll-Like Receptor 9; Molecular biology; Innate immune system; Transfection; Cell culture; Immune system; Microbiology; Gene expression; DNA methylation; Immunology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001221306,0.0002392015,0.0001420289,0.00009801553,0.00008885822,0.0002097321,0.00009420112,0.0002142604,0.001187952],"category_scores_gemma":[0.00009476531,0.00009475022,0.0002373181,0.00005134189,0.0001405604,0.0001590418,0.0001903824,0.0003085692,0.000505221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001373651,"about_ca_system_score_gemma":0.00009818091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001606185,"about_ca_topic_score_gemma":0.0002236067,"domain_scores_codex":[0.9998665,0.00003260841,0.00001182389,0.00002166553,0.00002518053,0.00004229209],"domain_scores_gemma":[0.9999297,0.00001228527,0.000025179,0.000006998646,0.00001337193,0.00001250778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007002754,0.00001064782,0.0002343664,0.00003275218,0.000002024473,0.00004305935,0.00000734915,0.0000124907,0.9991124,0.0000115923,0.00001318624,0.0004500321],"study_design_scores_gemma":[0.00002923534,0.0005827803,0.01666402,0.00001392929,0.00001505133,0.0007118505,0.00009401191,0.0005966751,0.9795197,0.00007218159,0.001694749,0.000005799889],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954025,0.001117939,0.002049894,0.00009565116,0.00002647773,0.00002780463,0.0002187728,0.00003367375,0.00102731],"genre_scores_gemma":[0.9948922,0.0007208191,0.00219161,0.0001048856,0.00001251646,0.00003916449,0.0003678932,0.000006164428,0.001664705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001187952,"threshold_uncertainty_score":0.00397408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009158591218771005,"score_gpt":0.2623716019286633,"score_spread":0.2532130107098923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}