{"id":"W2110156824","doi":"10.1200/jco.2013.49.6158","title":"Is Tremelimumab Beneficial in Advanced Melanoma?","year":2013,"lang":"en","type":"letter","venue":"Journal of Clinical Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Jonsson Comprehensive Cancer Center; University of California, Los Angeles","keywords":"Tremelimumab; Medicine; Melanoma; Oncology; Ipilimumab; Internal medicine; Cancer; Immunotherapy; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006325024,0.0002350838,0.0008596993,0.00030236,0.0006814701,0.0008056171,0.000447729,0.00521497,0.004985656],"category_scores_gemma":[0.004587259,0.0001373549,0.0005463212,0.0002967112,0.0006540471,0.001004062,0.0002441371,0.004830405,0.002386317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001099759,"about_ca_system_score_gemma":0.0008896658,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007787521,"about_ca_topic_score_gemma":0.002382817,"domain_scores_codex":[0.9996056,0.0001565595,0.00004422881,0.00003518858,0.00009549961,0.00006306169],"domain_scores_gemma":[0.9988253,0.0005693411,0.00007535846,0.00005215042,0.0002033264,0.0002744974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002648826,0.0004694881,0.01759154,0.0006418574,0.0001347644,0.01665313,0.0001044125,0.0007320615,0.003574782,0.004456691,0.5363849,0.4166076],"study_design_scores_gemma":[0.003072752,0.002429054,0.04404589,0.002442824,0.0003182896,0.03425917,0.0007177036,0.003258763,0.002157905,0.04089022,0.866311,0.00009645961],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0199994,0.02745119,0.0002153176,0.9316061,0.007175356,0.00003572414,0.00015235,0.00007281556,0.01329163],"genre_scores_gemma":[0.2609078,0.0451293,0.001736672,0.5888897,0.08542255,0.0001697902,0.00035855,0.00004797629,0.01733779],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.00521497,"threshold_uncertainty_score":0.01667869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1169966416220452,"score_gpt":0.4530544913705417,"score_spread":0.3360578497484965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}