{"id":"W2110195051","doi":"10.1074/jbc.m111.290882","title":"A Cav3.2/Syntaxin-1A Signaling Complex Controls T-type Channel Activity and Low-threshold Exocytosis","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Innovates; Vedecká Grantová Agentúra MŠVVaŠ SR a SAV; Universitat Pompeu Fabra; Ministerio de Ciencia e Innovación; Generalitat de Catalunya; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Vanderbilt University; York University; Alberta Innovates - Health Solutions; University of Toronto; Saint Louis University","keywords":"Exocytosis; STX1A; Syntaxin; Cell biology; Voltage-dependent calcium channel; Munc-18; T-type calcium channel; Biology; Calcium channel; N-type calcium channel; Synaptic vesicle; Chemistry; Calcium; Secretion; Biochemistry; Vesicle; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002616778,0.0001778385,0.0003031991,0.00001751595,0.00006330361,0.00001491338,0.0001706525,0.0003093621,0.0001569921],"category_scores_gemma":[0.00005535035,0.0001342733,0.0001683906,0.00005245742,0.0001253807,0.000006462841,0.0000474242,0.0002233636,0.000001332508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001346216,"about_ca_system_score_gemma":0.00004017432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005980017,"about_ca_topic_score_gemma":0.000001395555,"domain_scores_codex":[0.9991028,0.0000293911,0.0003088742,0.0002256505,0.0001169755,0.0002162945],"domain_scores_gemma":[0.999289,0.00001531127,0.0002510906,0.0001386622,0.00013871,0.0001672014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001002111,0.0001242445,0.004199984,0.00003005362,0.0000755525,0.00003706167,0.00003394064,0.000003807823,0.9942578,0.000002465008,0.00002242184,0.000210573],"study_design_scores_gemma":[0.000766585,0.0005571293,0.008250605,0.0000295358,0.00003746085,0.0001633318,0.00006398585,0.00004492305,0.988857,0.0000974647,0.0009396665,0.0001922586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970846,0.0007892338,0.001435036,0.00004399565,0.00006498412,0.00006336877,0.00001045547,0.00000686591,0.0005014807],"genre_scores_gemma":[0.9987863,0.0004318678,0.0002073204,0.0001051803,0.0003092841,0.000001894396,0.00009461342,0.00001051883,0.00005303326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005400732,"threshold_uncertainty_score":0.5475506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05048261210162124,"score_gpt":0.2420740274436158,"score_spread":0.1915914153419945,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}