{"id":"W2110238986","doi":"10.1093/cvr/cvp268","title":"Matrix metalloproteinase-2 and myocardial oxidative stress injury: beyond the matrix","year":2009,"lang":"en","type":"review","venue":"Cardiovascular Research","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":287,"is_retracted":false,"has_abstract":true,"ca_institutions":"Heritage Medical Research Clinic; University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; Heart and Stroke Foundation of Canada","keywords":"Matrix metalloproteinase; Proteases; Oxidative stress; Extracellular matrix; Cell biology; Intracellular; Proteolytic enzymes; Protease; Biology; Chemistry; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003393198,0.0006311255,0.001101407,0.001393877,0.0002677157,0.0008396971,0.0007041577,0.001048537,0.002532525],"category_scores_gemma":[0.0003915186,0.0001686389,0.0002998241,0.001764501,0.0004008737,0.001475238,0.0005702779,0.001139655,0.001796232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004939954,"about_ca_system_score_gemma":0.0008052752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007181865,"about_ca_topic_score_gemma":0.001342549,"domain_scores_codex":[0.9998858,0.00001875958,0.00001467499,0.00002031854,0.00004750559,0.00001289139],"domain_scores_gemma":[0.9998522,0.00005203712,0.00002312651,0.000005806514,0.00004399074,0.00002286458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000108734,0.00009248736,0.0003212038,0.01252112,0.000086122,0.000784783,0.0001269422,0.0003410387,0.006067133,0.005047658,0.03811266,0.9363902],"study_design_scores_gemma":[0.00001941287,0.00009933185,0.001504084,0.001793764,0.00005934171,0.003538461,0.000111266,0.00009376073,0.0008330282,0.003342034,0.9885888,0.00001667139],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001461202,0.998607,0.0001131231,0.0002550392,0.0002145121,0.000002106047,0.000005951032,0.000003980292,0.0006521221],"genre_scores_gemma":[0.0007252573,0.9979483,0.0001334331,0.0001366234,0.0001986674,0.000003330334,0.00001225602,9.114009e-7,0.0008412122],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002532525,"threshold_uncertainty_score":0.008472085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04772684147625723,"score_gpt":0.3800872341632778,"score_spread":0.3323603926870206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}