{"id":"W2110251267","doi":"10.1136/gut.2004.041426","title":"Increased epithelial uptake of protein antigens in the ileum of Crohn’s disease mediated by tumour necrosis factor α","year":2004,"lang":"en","type":"article","venue":"Gut","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":162,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto; McMaster University; St. Michael's Hospital","funders":"Canadian Institutes of Health Research; Vetenskapsrådet; Crohn's and Colitis Foundation of Canada; Crohn's and Colitis Foundation","keywords":"Horseradish peroxidase; Endosome; Ileum; Tumor necrosis factor alpha; Crohn's disease; Intestinal mucosa; Necrosis; Biology; Antigen; Peroxidase; Pathology; Molecular biology; Chemistry; Internal medicine; Endocrinology; Immunology; Medicine; Intracellular; Biochemistry; Enzyme; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001971839,0.0002385747,0.0004025157,0.0004405599,0.0001850139,0.0004215651,0.0001041155,0.0004197669,0.0009401543],"category_scores_gemma":[0.000360197,0.0002163744,0.0002553336,0.000204794,0.0003867954,0.0002703861,0.0003170499,0.0003796074,0.0001937478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002621666,"about_ca_system_score_gemma":0.00007318021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002226052,"about_ca_topic_score_gemma":0.0002632228,"domain_scores_codex":[0.9998301,0.00003239837,0.00001895361,0.00004239457,0.00004002175,0.0000360364],"domain_scores_gemma":[0.9996699,0.00005435245,0.0001155622,0.00003448374,0.00003966889,0.00008600795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001930556,0.00005218079,0.0451024,0.0001282923,0.0000265366,0.001034523,0.0001474713,0.00004001397,0.9491894,0.00002545678,0.00002912678,0.002294066],"study_design_scores_gemma":[0.00005519505,0.001769742,0.8869897,0.00001973735,0.00006644853,0.007967356,0.0003560696,0.0004155708,0.1014322,0.00007637122,0.0008427617,0.000009019654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990701,0.0006700664,0.0001147827,0.00001136205,0.000003217538,0.000002503774,0.00001325615,0.000005405682,0.000109373],"genre_scores_gemma":[0.9993222,0.0002800816,0.0001892295,0.00001034145,0.000003993618,0.000003025252,0.00004668971,0.000001674842,0.0001428261],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009401543,"threshold_uncertainty_score":0.003145099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007145731153270339,"score_gpt":0.2219158259761263,"score_spread":0.214770094822856,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}