{"id":"W2110256914","doi":"10.1242/dev.061770","title":"<i>Drosophila</i> Smt3 negatively regulates JNK signaling through sequestering Hipk in the nucleus","year":2011,"lang":"en","type":"article","venue":"Development","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Key Research and Development Program of China; Institute of Genetics; National Natural Science Foundation of China","keywords":"SUMO protein; Biology; Gene knockdown; Cell biology; Signal transduction; Ectopic expression; Ubiquitin; Apoptosis; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003264422,0.0001559972,0.0001092265,0.00002161627,0.0001062608,0.00002635667,0.0002748014,0.00008935285,0.00003300117],"category_scores_gemma":[0.00002389148,0.0001206365,0.00003756036,0.00008898154,0.00004954213,0.000007165042,0.0001225786,0.00009721361,0.00002806859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002135623,"about_ca_system_score_gemma":0.00007880983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002268306,"about_ca_topic_score_gemma":0.00002019608,"domain_scores_codex":[0.999027,0.00007592651,0.0002323233,0.0002717674,0.0001271086,0.0002658524],"domain_scores_gemma":[0.9996468,0.00001061412,0.00006605215,0.0002111806,0.00003229741,0.0000330329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001042571,0.0001304643,0.00304912,0.00005261832,0.00006151968,0.00004634666,0.02437485,0.00001486016,0.9634085,0.001158382,0.0003436655,0.007255365],"study_design_scores_gemma":[0.000260852,0.00006845306,0.007120618,0.00004303135,0.000003552229,0.00001963739,0.0003760951,0.000003459496,0.9512798,0.001031154,0.03958711,0.0002062318],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875575,0.0002644848,0.0003457033,0.0001073115,0.0000827862,0.0002380872,0.000004296836,0.0000176962,0.0113821],"genre_scores_gemma":[0.9837039,0.00003692488,0.01506903,0.0008438456,0.00008519319,0.00007187804,0.00003231588,0.0000192916,0.0001376071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03924344,"threshold_uncertainty_score":0.4919413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05476894183682688,"score_gpt":0.2467999113379975,"score_spread":0.1920309695011706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}