{"id":"W2110256914","doi":"10.1242/dev.061770","title":"<i>Drosophila</i> Smt3 negatively regulates JNK signaling through sequestering Hipk in the nucleus","year":2011,"lang":"en","type":"article","venue":"Development","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Key Research and Development Program of China; Institute of Genetics; National Natural Science Foundation of China","keywords":"SUMO protein; Biology; Gene knockdown; Cell biology; Signal transduction; Ectopic expression; Ubiquitin; Apoptosis; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006839984,0.0003293125,0.0001321342,0.0001581451,0.0002193379,0.0002541079,0.0001632406,0.0001288206,0.001223464],"category_scores_gemma":[0.00006817192,0.00009851469,0.0001968756,0.000109291,0.0002373273,0.0001445303,0.0002029419,0.000261904,0.0005814736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005804977,"about_ca_system_score_gemma":0.0002392617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001207883,"about_ca_topic_score_gemma":0.003113359,"domain_scores_codex":[0.9999392,0.00000953663,0.000006431274,0.0000125474,0.00001673752,0.00001555161],"domain_scores_gemma":[0.9999398,0.0000053986,0.00002631014,0.00000611766,0.000005976133,0.00001638414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000552011,0.000003268423,0.0002100781,0.00001996441,0.000002525569,0.00004257873,0.000004119406,0.00003349783,0.9989628,0.00009650832,0.00005485799,0.0005146276],"study_design_scores_gemma":[0.0000097454,0.00003431801,0.008635071,0.000004782938,0.000006888547,0.0002218796,0.00001896902,0.0008118419,0.988414,0.00007230301,0.001766902,0.000003225729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920779,0.001258843,0.002387353,0.0001766053,0.00002161064,0.000008744962,0.0007104657,0.0001513205,0.003207128],"genre_scores_gemma":[0.9958342,0.0004123404,0.001274086,0.00005143871,0.000005106833,0.00000806519,0.0004598083,0.00003250777,0.001922322],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001223464,"threshold_uncertainty_score":0.004211903,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05476894183682688,"score_gpt":0.2467999113379975,"score_spread":0.1920309695011706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}