{"id":"W2110271691","doi":"10.1128/ec.00265-08","title":"Transcriptional Profiling Identifies a Role for BrlA in the Response to Nitrogen Depletion and for StuA in the Regulation of Secondary Metabolite Clusters in <i>Aspergillus fumigatus</i>","year":2008,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":120,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health; McGill University; Burroughs Wellcome Fund","keywords":"Conidiation; Biology; Mutant; Aspergillus fumigatus; Gene; Ribosomal protein; Gene expression; Wild type; Regulation of gene expression; Downregulation and upregulation; Aspergillus nidulans; Cell biology; Molecular biology; Microbiology; Genetics; RNA; Ribosome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007369534,0.0003039258,0.0003019609,0.0002513871,0.0001653438,0.0003187541,0.0001610188,0.000219819,0.0007800118],"category_scores_gemma":[0.0001118269,0.0002109476,0.0003396094,0.0001871162,0.0001686196,0.0001567856,0.0002141792,0.0005168077,0.0005103778],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003802043,"about_ca_system_score_gemma":0.0002065333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002425641,"about_ca_topic_score_gemma":0.004125044,"domain_scores_codex":[0.9998434,0.00001016295,0.00001302753,0.00006181264,0.00003885302,0.00003278411],"domain_scores_gemma":[0.9998661,0.00001949989,0.00003798847,0.00001610181,0.00002442112,0.00003584117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003145088,0.000004136973,0.0003679925,0.000008287027,9.774041e-7,0.00001075599,0.000005931193,0.00001079544,0.9992821,0.00001199079,0.000011048,0.0002546026],"study_design_scores_gemma":[0.000009455393,0.0001627264,0.1395808,0.00001281878,0.00002480536,0.0003243455,0.0001268654,0.001493206,0.8562331,0.00006408957,0.001956583,0.00001120621],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930792,0.0009132939,0.00197571,0.000127398,0.00001260782,0.00001618077,0.002742632,0.0001125077,0.00102049],"genre_scores_gemma":[0.9895544,0.0003813149,0.002014837,0.0001479471,0.000008517333,0.0000351544,0.005263899,0.00005431657,0.002539595],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002425641,"threshold_uncertainty_score":0.004823089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01718974739352292,"score_gpt":0.2581430026423681,"score_spread":0.2409532552488452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}