{"id":"W2110334171","doi":"10.1093/hmg/ddp052","title":"Common variants in the region around Osterix are associated with bone mineral density and growth in childhood","year":2009,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":133,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Health and Medical Research Council; Medical Research Council; King's College London; University of Bristol; Canadian Institutes of Health Research; National Institute for Health and Care Research; Chronic Disease Research Foundation; Wellcome Trust","keywords":"Bone mineral; Longitudinal study; Biology; Body mass index; Single-nucleotide polymorphism; Population; Bone density; Endocrinology; Femoral neck; Internal medicine; Genome-wide association study; Osteoporosis; Demography; Genetics; Medicine; Genotype; Gene; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000346681,0.0005528811,0.0004830537,0.000673835,0.0003643208,0.0004760199,0.0004245253,0.000503219,0.001638035],"category_scores_gemma":[0.001275289,0.0002423336,0.0004776184,0.001358804,0.0004697753,0.0001502099,0.0004273364,0.000315094,0.0001494115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002786867,"about_ca_system_score_gemma":0.0002629759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01000221,"about_ca_topic_score_gemma":0.0116044,"domain_scores_codex":[0.9994686,0.00007970463,0.00006118094,0.0001864409,0.000144216,0.00005992674],"domain_scores_gemma":[0.9992181,0.0002327158,0.0004145521,0.00003238329,0.00004026546,0.00006203232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009948161,0.00004305521,0.9662198,0.0002100444,0.0009052117,0.001855517,0.0002988122,0.0006630855,0.01287442,0.0005465358,0.0005792512,0.01480953],"study_design_scores_gemma":[0.00002633029,0.00005790166,0.9960681,0.00003843738,0.000256497,0.001358846,0.00007448197,0.0004031335,0.0007315781,0.0002036058,0.0007753414,0.000005667383],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936156,0.003452731,0.0006990311,0.000111062,0.00001353265,0.00001210221,0.001047775,0.00003676535,0.001011459],"genre_scores_gemma":[0.996125,0.001275476,0.001548329,0.00004849426,0.00002064535,0.00001185018,0.0006052619,0.00001313561,0.0003516922],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01000221,"threshold_uncertainty_score":0.01988798,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01251696945344288,"score_gpt":0.2391510254964017,"score_spread":0.2266340560429588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}