{"id":"W2110334171","doi":"10.1093/hmg/ddp052","title":"Common variants in the region around Osterix are associated with bone mineral density and growth in childhood","year":2009,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":133,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Health and Medical Research Council; Medical Research Council; King's College London; University of Bristol; Canadian Institutes of Health Research; National Institute for Health and Care Research; Chronic Disease Research Foundation; Wellcome Trust","keywords":"Bone mineral; Longitudinal study; Biology; Body mass index; Single-nucleotide polymorphism; Population; Bone density; Endocrinology; Femoral neck; Internal medicine; Genome-wide association study; Osteoporosis; Demography; Genetics; Medicine; Genotype; Gene; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000310634,0.0001947451,0.0002627772,0.00006950586,0.0000934839,0.00003201632,0.0001720964,0.0002195589,8.202667e-7],"category_scores_gemma":[0.00009209347,0.0001622975,0.00004397754,0.0001573774,0.00007683722,0.000002723017,0.0000567192,0.0001755301,6.138882e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002467525,"about_ca_system_score_gemma":0.00002608633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003850819,"about_ca_topic_score_gemma":0.0007414641,"domain_scores_codex":[0.9985255,0.0003664324,0.0002898157,0.0003632829,0.0001274295,0.0003275167],"domain_scores_gemma":[0.9993935,0.00001957054,0.0001676328,0.0003136926,0.00005628685,0.00004932532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003868593,0.000384808,0.9446355,0.000005934906,0.00004673768,0.0002262194,0.0004071747,0.0002789861,0.05293173,0.0002084038,0.0002908644,0.0005449401],"study_design_scores_gemma":[0.001030026,0.0004752589,0.9952844,0.00002545381,0.00002463289,0.00007810412,0.0001172874,0.00009755327,0.0006888285,0.001951958,0.0000224378,0.0002040468],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978817,0.000631214,0.0003692338,0.0005527892,0.00001746744,0.0002654279,0.000003725708,0.000005856537,0.0002725809],"genre_scores_gemma":[0.9977793,0.0001211694,0.0002866277,0.001596849,0.00004460656,0.00001103229,0.0001180391,0.00001620767,0.00002620496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0522429,"threshold_uncertainty_score":0.6618299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01251696945344288,"score_gpt":0.2391510254964017,"score_spread":0.2266340560429588,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}