{"id":"W2110358975","doi":"10.1093/protein/gzg133","title":"Structural and functional analysis of a truncated form of Saccharomyces cerevisiae ATP sulfurylase: C-terminal domain essential for oligomer formation but not for activity","year":2003,"lang":"en","type":"article","venue":"Protein Engineering Design and Selection","topic":"Nitrogen and Sulfur Effects on Brassica","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Brookhaven National Laboratory; National Center for Research Resources; National Institute of General Medical Sciences","keywords":"Chemistry; Saccharomyces cerevisiae; Oligomer; Biochemistry; Stereochemistry; Enzyme; Dimer; Moiety; Pyrophosphate; Adenosine triphosphate; Yeast","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001293164,0.0004728612,0.0002128713,0.0001182172,0.000189426,0.0002204405,0.0002785956,0.0003204412,0.0005237699],"category_scores_gemma":[0.0001317468,0.0001161338,0.0002562958,0.0002076978,0.0002590584,0.0001157345,0.0001426316,0.0004306294,0.0003098628],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004391203,"about_ca_system_score_gemma":0.0002624995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002818378,"about_ca_topic_score_gemma":0.00298683,"domain_scores_codex":[0.9999267,0.00001261867,0.00001117905,0.00001446541,0.00002476063,0.00001018057],"domain_scores_gemma":[0.9998724,0.00002535089,0.00003464355,0.00001369094,0.0000211177,0.00003270484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001334162,0.00004282052,0.0002093453,0.00003290824,0.000007860033,0.0001427779,0.00002819649,0.0003044004,0.9981988,0.0001267865,0.00003076142,0.0007419352],"study_design_scores_gemma":[0.00004701577,0.0002548039,0.008806081,0.00001049104,0.00005377102,0.0009094219,0.00009341147,0.004516965,0.9811891,0.00008719305,0.004013882,0.00001782485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971645,0.0003354242,0.001508281,0.00004246274,0.00001348239,0.00001213298,0.0005776081,0.0000245338,0.0003216327],"genre_scores_gemma":[0.9938666,0.0003163559,0.002497344,0.00003367648,0.000006012972,0.00001324942,0.002149323,0.00003117762,0.001086156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002818378,"threshold_uncertainty_score":0.005604029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008935975907537204,"score_gpt":0.2197959962001529,"score_spread":0.2108600202926157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}