{"id":"W2110358975","doi":"10.1093/protein/gzg133","title":"Structural and functional analysis of a truncated form of Saccharomyces cerevisiae ATP sulfurylase: C-terminal domain essential for oligomer formation but not for activity","year":2003,"lang":"en","type":"article","venue":"Protein Engineering Design and Selection","topic":"Nitrogen and Sulfur Effects on Brassica","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Brookhaven National Laboratory; National Center for Research Resources; National Institute of General Medical Sciences","keywords":"Chemistry; Saccharomyces cerevisiae; Oligomer; Biochemistry; Stereochemistry; Enzyme; Dimer; Moiety; Pyrophosphate; Adenosine triphosphate; Yeast","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002161444,0.0001159283,0.000197371,0.0001371325,0.00005992334,0.00001419515,0.00002269648,0.00009166246,0.000002861827],"category_scores_gemma":[0.00007039106,0.0001100869,0.00008875621,0.0001611774,0.00002198762,0.00001906181,0.000006352791,0.00003469847,2.35212e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001133119,"about_ca_system_score_gemma":0.00002390278,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005076463,"about_ca_topic_score_gemma":0.000003084552,"domain_scores_codex":[0.9994367,0.00003161115,0.0001635531,0.0001702834,0.00006926688,0.0001285704],"domain_scores_gemma":[0.9996823,0.00003545209,0.00009812631,0.00005121399,0.00009663142,0.00003629795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005571921,0.00001525412,0.00007458962,0.0002177411,0.0002543789,5.939749e-8,0.00003539181,0.0009669127,0.9963061,0.000240557,0.000004812338,0.001327051],"study_design_scores_gemma":[0.0007390518,0.000405568,0.001713588,0.000009913419,0.0001777385,0.00000978164,0.000007906725,0.07613365,0.9205544,0.00007001554,0.00006831109,0.0001100574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5647724,0.0000609606,0.4347276,0.000005717445,0.00001491573,0.0003971829,0.00001559646,0.000004991316,5.952917e-7],"genre_scores_gemma":[0.9850174,0.000009869176,0.01469899,0.000003373274,0.00003218012,0.0001537353,0.00005496588,0.00001090516,0.00001854241],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.420245,"threshold_uncertainty_score":0.4489212,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008935975907537204,"score_gpt":0.2197959962001529,"score_spread":0.2108600202926157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}