{"id":"W2110368472","doi":"10.1158/0008-5472.can-13-3021","title":"Ly49 Family Receptors Are Required for Cancer Immunosurveillance Mediated by Natural Killer Cells","year":2014,"lang":"en","type":"article","venue":"Cancer Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Immunoediting; Immunosurveillance; Biology; NKG2D; Natural killer cell; MHC class I; Immune system; Cancer research; Receptor; Major histocompatibility complex; Interleukin 12; Lymphokine-activated killer cell; Cancer cell; Immunology; Interleukin 21; Cell biology; Cancer; Cytotoxic T cell; Immunotherapy; T cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001023297,0.0002386393,0.0002694319,0.0001591614,0.0001196596,0.0003760004,0.000211663,0.0003463738,0.001922572],"category_scores_gemma":[0.000302353,0.0001371961,0.0001915578,0.00006940374,0.0001877109,0.0002372904,0.0002391808,0.0004714651,0.001042409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002070302,"about_ca_system_score_gemma":0.0001356035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003032509,"about_ca_topic_score_gemma":0.0002327399,"domain_scores_codex":[0.999781,0.00004040531,0.00002446895,0.00003619357,0.00005380374,0.00006432517],"domain_scores_gemma":[0.9997076,0.00004800557,0.0000894502,0.0000459143,0.00002729959,0.00008167892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006988048,0.00001022327,0.0003237311,0.00001002625,0.0000017622,0.00007476669,0.00000450404,0.00002943255,0.9988577,0.00007483616,0.00002427312,0.0005189024],"study_design_scores_gemma":[0.00004940266,0.0002460879,0.024795,0.000006983106,0.00001825479,0.001846233,0.00004571554,0.001810825,0.9664405,0.0001394682,0.004590244,0.00001128487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929668,0.001946647,0.003077514,0.0001067076,0.00003524933,0.00002720373,0.0004465195,0.0001673336,0.001226105],"genre_scores_gemma":[0.9971765,0.0003407922,0.000833251,0.00002418853,0.00001179113,0.00002980306,0.0005509216,0.00002434841,0.001008391],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001922572,"threshold_uncertainty_score":0.006431639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0359361781749221,"score_gpt":0.3369864935975878,"score_spread":0.3010503154226657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}