{"id":"W2110368472","doi":"10.1158/0008-5472.can-13-3021","title":"Ly49 Family Receptors Are Required for Cancer Immunosurveillance Mediated by Natural Killer Cells","year":2014,"lang":"en","type":"article","venue":"Cancer Research","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Immunoediting; Immunosurveillance; Biology; NKG2D; Natural killer cell; MHC class I; Immune system; Cancer research; Receptor; Major histocompatibility complex; Interleukin 12; Lymphokine-activated killer cell; Cancer cell; Immunology; Interleukin 21; Cell biology; Cancer; Cytotoxic T cell; Immunotherapy; T cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0009637068,0.0002096124,0.0003326509,0.00017881,0.0004856412,0.00004634413,0.0003716957,0.000299287,0.00282698],"category_scores_gemma":[0.0003647317,0.0001824481,0.0001233985,0.0003334073,0.0003013984,0.0001590954,0.00008805547,0.000778371,0.0009098842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003678038,"about_ca_system_score_gemma":0.0001385535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0015817,"about_ca_topic_score_gemma":0.0001903611,"domain_scores_codex":[0.9976739,0.0005833966,0.0003405126,0.0004947837,0.0001302696,0.0007770981],"domain_scores_gemma":[0.9981203,0.0006268488,0.0001477221,0.0003724248,0.0006897002,0.00004297737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004758069,0.00002774895,0.0002106248,0.00002106391,0.0000763514,1.171614e-7,0.00009041134,0.000003580012,0.5314107,0.0000159166,0.463453,0.004214636],"study_design_scores_gemma":[0.001229888,0.0001307296,0.0007457759,0.00006412723,0.000006524097,0.000001004637,0.0002882376,0.0000289557,0.2437052,0.00001097153,0.7536106,0.0001780145],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.816615,0.07311025,0.0003492073,0.005209992,0.09861325,0.002005179,0.0001593659,0.0003477806,0.003589938],"genre_scores_gemma":[0.8044156,0.003839906,0.00001127183,0.0007008596,0.0002419058,0.0007635562,0.0004498584,0.00005535141,0.1895217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2901575,"threshold_uncertainty_score":0.999868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0359361781749221,"score_gpt":0.3369864935975878,"score_spread":0.3010503154226657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}