{"id":"W2110405430","doi":"10.1242/dmm.002642","title":"A Drosophila model of Menkes disease reveals a role for DmATP7 in copper absorption and neurodevelopment","year":2009,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"Trace Elements in Health","field":"Nursing","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Menkes disease; Drosophila (subgenus); Copper; Absorption (acoustics); Biology; Neuroscience; Copper metabolism; Cell biology; Genetics; Chemistry; Physics; Optics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003753825,0.0002816181,0.0003531948,0.0002116755,0.0001172632,0.00003381428,0.0001770641,0.00006930968,0.000005011084],"category_scores_gemma":[0.00006527433,0.0002971851,0.00009268287,0.000132755,0.00002915885,0.000354063,0.00004318528,0.0001095998,0.000001664791],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001487108,"about_ca_system_score_gemma":0.0001268096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001119863,"about_ca_topic_score_gemma":0.000005849003,"domain_scores_codex":[0.9977905,0.00007994253,0.0005858782,0.000592639,0.0004425281,0.0005085618],"domain_scores_gemma":[0.998796,0.00004526725,0.0001772964,0.0003909793,0.00009238919,0.0004980624],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.01402151,0.003892584,0.001601898,0.002059141,0.00006059839,0.00002748109,0.006530867,0.376582,0.1795104,0.3842496,0.0008825876,0.03058132],"study_design_scores_gemma":[0.001020221,0.000115034,0.004606797,0.0001453705,0.00005548828,2.984904e-7,0.00004072085,0.4717601,0.0007931208,0.5212597,0.000005288891,0.0001978312],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9375386,0.0005978795,0.05542365,0.003435573,0.0001840643,0.002233909,0.0004145238,0.0001215512,0.00005022535],"genre_scores_gemma":[0.9813823,0.00004918934,0.01647009,0.001643365,0.00003122401,0.0002632873,0.00006804056,0.00004965317,0.00004281464],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1787173,"threshold_uncertainty_score":0.999948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03102720698108537,"score_gpt":0.2860680938342651,"score_spread":0.2550408868531797,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}