{"id":"W2110410730","doi":"10.1111/j.1471-4159.2007.04870.x","title":"Post‐synaptic density perturbs insulin‐induced Kv1.3 channel modulation via a clustering mechanism involving the SH<sub>3</sub> domain","year":2007,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Olfactory and Sensory Function Studies","field":"Neuroscience","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Deafness and Other Communication Disorders; University of British Columbia","keywords":"PDZ domain; Guanylate kinase; Signal transducing adaptor protein; Biology; Phosphorylation; Protein kinase domain; Cell biology; Biochemistry; Membrane protein","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009174019,0.0002375811,0.0001765967,0.00007567515,0.0001034145,0.0001997948,0.0003602834,0.0002212062,0.001028822],"category_scores_gemma":[0.0001130136,0.0001119894,0.0002088084,0.00007387061,0.0002596234,0.0002028575,0.0001670703,0.0006877361,0.0002207257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002772443,"about_ca_system_score_gemma":0.0001210802,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004977643,"about_ca_topic_score_gemma":0.000572537,"domain_scores_codex":[0.9999032,0.0000170255,0.00001322664,0.0000163396,0.00001920173,0.00003104967],"domain_scores_gemma":[0.9999087,0.00001711702,0.00002666091,0.00001184622,0.000007577307,0.00002801115],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002110548,0.00004675541,0.0001101745,0.00002187909,0.000008185668,0.00004966282,0.000007746118,0.00003396115,0.998952,0.00007893817,0.00003088334,0.0004486089],"study_design_scores_gemma":[0.0000518159,0.0005451856,0.009794969,0.000006726621,0.00003427704,0.0002603578,0.00004687422,0.001751677,0.9866617,0.000114455,0.0007261285,0.00000576442],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981064,0.0002847722,0.0007446187,0.00006964609,0.00002739465,0.00001098667,0.0001019754,0.00004483535,0.0006094029],"genre_scores_gemma":[0.9987583,0.0001984643,0.0003873036,0.00004499961,0.000005102342,0.00001640696,0.000102604,0.000009188035,0.00047761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001028822,"threshold_uncertainty_score":0.003441811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05682785544439765,"score_gpt":0.2412398168873141,"score_spread":0.1844119614429165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}