{"id":"W2110415772","doi":"10.1139/o08-106","title":"Signaling and apoptosis differences between severe hypoxia and desferoxamine treatment of human epithelial cells","year":2008,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"","keywords":"Apoptosis; Protein kinase B; Hypoxia (environmental); HeLa; Biology; Cell biology; Programmed cell death; Cancer research; Cell culture; Cell cycle; PI3K/AKT/mTOR pathway; Cell growth; Cell cycle checkpoint; Chemistry; Biochemistry; Genetics; Oxygen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013112,0.0001868766,0.0002372798,0.0002042822,0.0001394317,0.000228876,0.00008914041,0.000285055,0.001014084],"category_scores_gemma":[0.0001363957,0.0001239082,0.0002573642,0.0001704967,0.0001151814,0.0001656566,0.0001255788,0.0002592264,0.0001800148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002545663,"about_ca_system_score_gemma":0.0001580958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006529979,"about_ca_topic_score_gemma":0.0009167573,"domain_scores_codex":[0.999855,0.00003569855,0.00001501848,0.00002278189,0.00003052591,0.00004094718],"domain_scores_gemma":[0.9999199,0.00001626414,0.00002136233,0.00001046417,0.00001300263,0.00001901752],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004276593,0.00002550901,0.0007054778,0.00003795412,0.000009915683,0.00008070274,0.00003774394,0.00003628601,0.99651,0.0001053542,0.00003558224,0.00198789],"study_design_scores_gemma":[0.00003268263,0.000925909,0.03187292,0.00001067995,0.00002623983,0.0008287787,0.000083263,0.000253784,0.9624291,0.00007688506,0.003453605,0.000006059422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917558,0.004883979,0.001228802,0.000118826,0.00002243602,0.0000288521,0.0003565432,0.00002463501,0.001580137],"genre_scores_gemma":[0.9956255,0.001648744,0.0007102197,0.00008394998,0.00001253052,0.00003379284,0.0005886359,0.000004803666,0.001291801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001014084,"threshold_uncertainty_score":0.003392458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01749936374692917,"score_gpt":0.2324408143267704,"score_spread":0.2149414505798412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}