{"id":"W2110419376","doi":"10.1533/abbi.2004.0018","title":"Deconjugation of Bile Acids with Immobilized Genetically Engineered <i>Lactobacillus plantarum</i> 80(pCBH1)","year":2005,"lang":"en","type":"article","venue":"Applied Bionics and Biomechanics","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; U.S. Food and Drug Administration; Canadian Institutes of Health Research; Bristol-Myers Squibb","keywords":"Hydrolysis; Biochemistry; Chemistry; Deoxycholic acid; Bile acid; Lactobacillus plantarum; Glycocholic acid; In vitro; Salt (chemistry); Bile Salt Export Pump; Amino acid; Genetically engineered; Bacteria; Biology; Lactic acid; Cholic acid; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001564574,0.0001752753,0.0003241133,0.0001232708,0.00004642671,0.00001849099,0.00005157367,0.0001464191,0.00009609746],"category_scores_gemma":[0.00001666872,0.0001249932,0.00004721044,0.0002724697,0.00005859451,0.00002889386,0.00003002408,0.00009224161,0.00002045495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003674564,"about_ca_system_score_gemma":0.00008344771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006376462,"about_ca_topic_score_gemma":0.000003898228,"domain_scores_codex":[0.9990124,0.000007812479,0.000289141,0.0002568502,0.0002162798,0.0002175876],"domain_scores_gemma":[0.9993792,0.00005497002,0.00009178829,0.0002313555,0.00008294889,0.000159705],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007118105,0.0002306683,0.0001631095,0.0001077267,0.0001288558,0.000002264558,0.00007836553,0.000009590301,0.9541188,0.01214985,0.00018541,0.03211352],"study_design_scores_gemma":[0.007047089,0.001418315,0.0004285108,0.00009491538,0.0003324682,0.0000783842,0.0002208342,0.01363796,0.9478837,0.0008843782,0.02758345,0.0003899996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931102,0.0005387038,0.003206679,0.0004187039,0.00006019676,0.0004464697,0.00004420646,0.00006909607,0.002105748],"genre_scores_gemma":[0.98824,0.0003755806,0.01054022,0.0005429817,0.00006367266,0.00002242924,0.0001117081,0.00001938564,0.00008400203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03172352,"threshold_uncertainty_score":0.5097076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006877342754304845,"score_gpt":0.20231595347745,"score_spread":0.1954386107231452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}