{"id":"W2110422767","doi":"10.1177/1933719113492212","title":"Enhanced Trimethylation of Histone H3 Mediates Impaired Expression of Hepatic Glucose 6-Phosphatase Expression in Offspring From Rat Dams Exposed to Hypoxia During Pregnancy","year":2013,"lang":"en","type":"article","venue":"Reproductive Sciences","topic":"Birth, Development, and Health","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children’s Health Research Institute; Women and Children’s Health Research Institute; University of Alberta; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Histone H3; Offspring; Epigenetics; Biology; Internal medicine; Endocrinology; Histone; Hypoxia (environmental); Gluconeogenesis; Epigenome; Histone methylation; Methylation; DNA methylation; Gene expression; Pregnancy; Chemistry; Medicine; Biochemistry; Gene; Oxygen; Metabolism; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006393065,0.0001838739,0.0005224931,0.0003439322,0.0001290689,0.00001142855,0.0001992675,0.00007650101,0.00009762307],"category_scores_gemma":[0.001087236,0.0001424814,0.00005215498,0.0007699682,0.0002313416,0.0005063368,0.0001126878,0.0001304227,0.0000103221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001443438,"about_ca_system_score_gemma":0.0002873313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006659419,"about_ca_topic_score_gemma":0.00002261891,"domain_scores_codex":[0.9973615,0.0001361622,0.0007357239,0.0008395008,0.0006000393,0.0003270774],"domain_scores_gemma":[0.9985232,0.0001289412,0.0004532174,0.0005080519,0.0002211704,0.0001653832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001886358,0.0002260042,0.02087317,0.00020939,0.0000051079,0.0000030633,0.006976794,0.0000335931,0.9673918,0.00002404678,0.00001759925,0.004050754],"study_design_scores_gemma":[0.0008065394,0.0002099562,0.2629934,0.001686433,0.00000801031,0.000001028927,0.000879627,0.0000420207,0.7323142,0.0009510877,8.957365e-7,0.0001068607],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937652,0.004048024,0.0002094962,0.0002328009,0.0002951224,0.001261175,0.00000630307,0.00003269036,0.000149188],"genre_scores_gemma":[0.9846138,0.001875664,0.01327636,0.00001314245,0.000073899,0.00009141846,0.00001350251,0.00001254663,0.00002968195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2421202,"threshold_uncertainty_score":0.5810222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02890544861910911,"score_gpt":0.3191574635393382,"score_spread":0.2902520149202291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}