{"id":"W2110422767","doi":"10.1177/1933719113492212","title":"Enhanced Trimethylation of Histone H3 Mediates Impaired Expression of Hepatic Glucose 6-Phosphatase Expression in Offspring From Rat Dams Exposed to Hypoxia During Pregnancy","year":2013,"lang":"en","type":"article","venue":"Reproductive Sciences","topic":"Birth, Development, and Health","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children’s Health Research Institute; Women and Children’s Health Research Institute; University of Alberta; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Histone H3; Offspring; Epigenetics; Biology; Internal medicine; Endocrinology; Histone; Hypoxia (environmental); Gluconeogenesis; Epigenome; Histone methylation; Methylation; DNA methylation; Gene expression; Pregnancy; Chemistry; Medicine; Biochemistry; Gene; Oxygen; Metabolism; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001319623,0.0003009427,0.0003441413,0.0003182143,0.0002270641,0.000224263,0.0002636367,0.0002380591,0.001724816],"category_scores_gemma":[0.0001857645,0.0003727583,0.0002217866,0.0001311759,0.0004856067,0.0002291271,0.0003119573,0.0006812935,0.0002238458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002379314,"about_ca_system_score_gemma":0.0002784708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001712138,"about_ca_topic_score_gemma":0.002355818,"domain_scores_codex":[0.9998734,0.00001640277,0.000007035265,0.00003022356,0.00002224416,0.00005062329],"domain_scores_gemma":[0.999822,0.00001985748,0.00006170942,0.00002286432,0.00001397111,0.00005964028],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008214478,0.00003629499,0.001484385,0.0000196855,0.000009715095,0.0001442087,0.0001080521,0.00001810106,0.9965532,0.00008179124,0.0000212442,0.0007019032],"study_design_scores_gemma":[0.00004194359,0.0007277416,0.06078455,0.00001131753,0.00007711009,0.0004954911,0.0004405685,0.0005584841,0.9359261,0.0001720177,0.0007515855,0.00001312132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983261,0.0003103532,0.0008882979,0.00007273795,0.0000212,0.000004299911,0.00008741967,0.00001639218,0.0002731785],"genre_scores_gemma":[0.9965456,0.0004571283,0.0004821402,0.00004377073,0.00001077906,0.00002521142,0.0001991366,0.00002140996,0.002214783],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001724816,"threshold_uncertainty_score":0.005770087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02890544861910911,"score_gpt":0.3191574635393382,"score_spread":0.2902520149202291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}