{"id":"W2110438110","doi":"10.1093/toxsci/kfr109","title":"A Safety Evaluation of DAS181, a Sialidase Fusion Protein, in Rodents","year":2011,"lang":"en","type":"article","venue":"Toxicological Sciences","topic":"Inhalation and Respiratory Drug Delivery","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Anthropology Society","funders":"National Institute of Allergy and Infectious Diseases; U.S. Public Health Service; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Inhalation; Toxicity; Alkaline phosphatase; Beagle; Physiology; Medicine; Respiratory system; Pathology; Respiratory tract; Inhalation exposure; Internal medicine; Pharmacology; Immunology; Andrology; Endocrinology; Biology; Biochemistry; Anesthesia; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000448425,0.0006536785,0.0004307841,0.0004695432,0.0003259062,0.0003504229,0.000400048,0.0006244287,0.001167369],"category_scores_gemma":[0.0003526954,0.0002265698,0.0005842758,0.0002047168,0.0003971298,0.0004080282,0.0001836392,0.0009024049,0.0003555233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003100927,"about_ca_system_score_gemma":0.0005061749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007142618,"about_ca_topic_score_gemma":0.001130348,"domain_scores_codex":[0.9997312,0.00006490687,0.00001491887,0.00007911571,0.00006713272,0.00004276455],"domain_scores_gemma":[0.9995757,0.00003553229,0.000123248,0.00005166862,0.0000951386,0.0001188406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003813631,0.002574267,0.001904042,0.0002667403,0.00007275827,0.0002380411,0.0001044988,0.0005536691,0.9693672,0.0001736797,0.0003942701,0.02053724],"study_design_scores_gemma":[0.0008842024,0.265636,0.01169886,0.00009419132,0.0003144136,0.001344822,0.000264063,0.001273396,0.7042143,0.0002829341,0.01393878,0.00005404282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910716,0.001811204,0.003864059,0.0002278648,0.00006333053,0.0003234177,0.0008004298,0.0001364653,0.001701542],"genre_scores_gemma":[0.9841202,0.00362968,0.005304797,0.000318397,0.00004178073,0.0004387007,0.001264217,0.00003984335,0.00484241],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001167369,"threshold_uncertainty_score":0.003905177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.199580531020135,"score_gpt":0.368286682770705,"score_spread":0.1687061517505699,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}