{"id":"W2110470249","doi":"10.1093/nar/gkv001","title":"A defense-offense multi-layered regulatory switch in a pathogenic bacterium","year":2015,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Azrieli Foundation; Agence Nationale de la Recherche","keywords":"Biology; Offensive; Gene; Quorum sensing; Computational biology; Regulation of gene expression; Gene expression; Cell biology; Transcription factor; Regulator; Genetics; Synthetic biology; Transcriptional regulation; Virulence","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001561901,0.000161551,0.0002106383,0.0001168021,0.0002133395,0.0004010203,0.0002661425,0.0002853517,0.0005968536],"category_scores_gemma":[0.0003319368,0.0001400953,0.0002247545,0.00007825172,0.0004067751,0.0002855008,0.0002868787,0.0002399537,0.00007360861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002770323,"about_ca_system_score_gemma":0.0003603648,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000797341,"about_ca_topic_score_gemma":0.0006639947,"domain_scores_codex":[0.9999473,0.0000109031,0.000002125284,0.00001774656,0.00001172672,0.00001026669],"domain_scores_gemma":[0.9999137,0.00003660795,0.0000177811,0.000006593107,0.000006977376,0.00001833778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000219849,0.0001016607,0.00351732,0.00007845203,0.0000602318,0.0002617901,0.00008695517,0.2226424,0.7398084,0.02147771,0.0001360595,0.01160921],"study_design_scores_gemma":[0.00004319982,0.0002163221,0.002405949,0.000003267045,0.00003377171,0.0001163086,0.00003414651,0.9405738,0.0507269,0.005034026,0.0007888654,0.00002342644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9441438,0.0001121947,0.05411808,0.00007021493,0.00001351035,0.00001351467,0.00002977273,0.0001563986,0.001342577],"genre_scores_gemma":[0.993427,0.00006149127,0.006091205,0.00001830625,0.000002877261,0.00001337096,0.00002125728,0.000008048618,0.0003565125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000797341,"threshold_uncertainty_score":0.002009988,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0648744058420101,"score_gpt":0.325200960843687,"score_spread":0.260326555001677,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}