{"id":"W2110653793","doi":"10.3791/51222","title":"High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses","year":2014,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; Institut national de la recherche scientifique","keywords":"Chikungunya; Virology; Biology; Measles virus; Virus; Dengue virus; Viral replication; Dengue fever; RNA; RNA virus; Computational biology; Measles; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003306182,0.0001994899,0.0007770772,0.0001400253,0.0000486612,0.00002314709,0.0001598113,0.0001009198,0.0001556171],"category_scores_gemma":[0.0002612807,0.0001586222,0.000488852,0.0001096778,0.00006591646,0.0001413776,0.00004431197,0.0001437718,0.000003196631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006169188,"about_ca_system_score_gemma":0.00008434203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003326431,"about_ca_topic_score_gemma":2.489895e-7,"domain_scores_codex":[0.9980202,0.00005815521,0.0009028406,0.0001878461,0.0005391308,0.000291834],"domain_scores_gemma":[0.9984725,0.0001105549,0.0007029006,0.0002196565,0.0002200461,0.0002744063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005690917,0.0006928434,0.001205635,0.000102634,0.0005080449,0.00001354125,0.0003051228,0.00000720892,0.9797588,0.001300422,0.004648829,0.005765999],"study_design_scores_gemma":[0.0148128,0.001557898,0.0005341996,0.0003997609,0.0003168355,0.0000311625,0.0002474731,0.000412261,0.9736093,0.0003034117,0.007613915,0.0001609501],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9796109,0.001751441,0.01726353,0.0003639203,0.0004944602,0.0003417143,0.00001050165,0.00001884471,0.0001447169],"genre_scores_gemma":[0.9901267,0.0000358515,0.007836539,0.000728299,0.001152832,0.00001550578,0.000006601493,0.00004032218,0.00005732335],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01051585,"threshold_uncertainty_score":0.6468428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03152995006897745,"score_gpt":0.4139211618708872,"score_spread":0.3823912118019098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}