{"id":"W2110653793","doi":"10.3791/51222","title":"High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses","year":2014,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; Institut national de la recherche scientifique","keywords":"Chikungunya; Virology; Biology; Measles virus; Virus; Dengue virus; Viral replication; Dengue fever; RNA; RNA virus; Computational biology; Measles; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007498118,0.001064981,0.001351771,0.001116682,0.0004204275,0.000854782,0.0007742234,0.0006357648,0.001650232],"category_scores_gemma":[0.0004225514,0.0004028338,0.0009572333,0.0009714715,0.0002620904,0.0004765175,0.0005819194,0.0008150039,0.0009285444],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004439123,"about_ca_system_score_gemma":0.0005185631,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007794533,"about_ca_topic_score_gemma":0.002301162,"domain_scores_codex":[0.9992648,0.0001464953,0.00005110056,0.0001186914,0.0003464164,0.00007254852],"domain_scores_gemma":[0.9997594,0.00009776612,0.00003412547,0.00002858763,0.00005175392,0.000028489],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002009142,0.0004618173,0.0006081881,0.0003593781,0.00009005863,0.0001126389,0.0000318885,0.001375619,0.9810593,0.0001186154,0.0005440327,0.01503755],"study_design_scores_gemma":[0.0001028781,0.002360544,0.003063259,0.0000235235,0.0001602313,0.00041928,0.00003496792,0.004005175,0.9837141,0.0001123607,0.005961462,0.00004232382],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.8472078,0.01897806,0.1063362,0.0007478561,0.000190876,0.003110834,0.01227999,0.002939017,0.008209284],"genre_scores_gemma":[0.8359352,0.0208993,0.1176133,0.0003849249,0.00009104179,0.00192465,0.01230425,0.0002187631,0.01062849],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001650232,"threshold_uncertainty_score":0.005520642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03152995006897745,"score_gpt":0.4139211618708872,"score_spread":0.3823912118019098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}