{"id":"W2110664610","doi":"10.1016/j.cbi.2006.01.001","title":"Evaluation of various housekeeping genes for their applicability for normalization of mRNA expression in dioxin-treated rats","year":2006,"lang":"en","type":"article","venue":"Chemico-Biological Interactions","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Academy of Finland","keywords":"Housekeeping gene; Glyceraldehyde 3-phosphate dehydrogenase; Reference genes; Gene; Gene expression; Biology; Normalization (sociology); Real-time polymerase chain reaction; Microarray; Microarray analysis techniques; Database normalization; Messenger RNA; Gene expression profiling; Molecular biology; Computational biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004472459,0.0001250825,0.000195477,0.00003841717,0.00005164458,0.000004256249,0.0001344039,0.0002162796,0.000009677639],"category_scores_gemma":[0.0001723361,0.0001029161,0.0001437422,0.00009952379,0.00009389591,0.000004969373,0.00005032212,0.00005380113,1.673171e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000353266,"about_ca_system_score_gemma":0.00003172713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002834749,"about_ca_topic_score_gemma":0.00004267554,"domain_scores_codex":[0.9989865,0.0000698981,0.0004126333,0.0003258397,0.00006225512,0.0001429126],"domain_scores_gemma":[0.9989632,0.00008038514,0.000234343,0.0002614818,0.0004400698,0.00002052251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008576229,0.0002620426,0.003077383,0.00001855847,0.00001668749,2.044323e-8,0.000007252309,0.0003393467,0.9930722,0.0001695056,0.0001995786,0.002751675],"study_design_scores_gemma":[0.0004129559,0.0001381206,0.002350881,0.00001956405,0.00003094246,0.000002352405,0.00002197938,0.001644162,0.9900071,0.002574965,0.00269108,0.0001058919],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.891293,0.0002635838,0.1068924,0.00003950722,0.00002653934,0.001106956,0.0001417087,0.00001761748,0.0002186875],"genre_scores_gemma":[0.9923165,0.00006517809,0.004757844,0.00002188795,0.0000707549,0.001326333,0.001413908,0.00001135918,0.00001627967],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1021345,"threshold_uncertainty_score":0.4196795,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04028104914456983,"score_gpt":0.3309104562177677,"score_spread":0.2906294070731979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}