{"id":"W2110669425","doi":"10.1093/nar/gkn1057","title":"Transcriptional control by adenovirus E1A conserved region 3 via p300/CBP","year":2009,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Transcriptional regulation; Activator (genetics); Molecular biology; Gene knockdown; Gene isoform; Transcription (linguistics); Mutant; Transcription factor; Adenoviridae; Gene; Regulation of gene expression; Cell biology; Genetics; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001743722,0.0003571206,0.000193877,0.0002778616,0.0001961353,0.0004374088,0.0003026532,0.0001777361,0.000865364],"category_scores_gemma":[0.0001163531,0.0001759079,0.0003531601,0.0001943628,0.0003172232,0.000152527,0.0003143789,0.0006607245,0.000568938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007956438,"about_ca_system_score_gemma":0.0004150021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002128518,"about_ca_topic_score_gemma":0.002504386,"domain_scores_codex":[0.9998511,0.0000205262,0.00001231112,0.0000361312,0.00004212226,0.00003789899],"domain_scores_gemma":[0.9999102,0.00001600327,0.00002434304,0.00001061971,0.00001150384,0.00002727644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001366256,0.00001936811,0.0001299873,0.00003136173,0.000002891682,0.00003755448,0.000009873187,0.00004863318,0.9982091,0.0001525845,0.0000498775,0.001172212],"study_design_scores_gemma":[0.00007137485,0.0001707628,0.008488135,0.00001162476,0.00001637529,0.0003350599,0.0000408652,0.003709831,0.9821751,0.0001822136,0.00478746,0.00001116311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884184,0.003026035,0.005054029,0.0001312855,0.0000332069,0.00003909372,0.0005309265,0.0002107489,0.002556235],"genre_scores_gemma":[0.9915683,0.0008212243,0.003627085,0.00004362385,0.000007571391,0.00003971652,0.0007166316,0.00002570827,0.003150135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002128518,"threshold_uncertainty_score":0.005772829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03877165206194443,"score_gpt":0.3338683864885283,"score_spread":0.2950967344265839,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}